Cancers, Vol. 15, Pages 5355: Endoscopic Ultrasound-Guided Fiducial Placement for Stereotactic Body Radiation Therapy in Patients with Pancreatic Cancer

Cancers, Vol. 15, Pages 5355: Endoscopic Ultrasound-Guided Fiducial Placement for Stereotactic Body Radiation Therapy in Patients with Pancreatic Cancer Cancers doi: 10.3390/cancers15225355 Authors: Irina M. Cazacu Ben S. Singh Rachael M. Martin-Paulpeter Sam Beddar Stephen Chun Emma B. Holliday Albert C. Koong Prajnan Das Eugene J. Koay Cullen Taniguchi Joseph M. Herman Manoop S. Bhutani Accurate delivery of stereotactic body radiotherapy (SBRT) to pancreatic tumors relies on successful EUS-guided placement of fiducial markers. The aim of this study is to report the technical feasibility and safety of EUS-guided fiducial placement and to evaluate the characteristics and technical benefit of SBRT in a cohort of patients with pancreatic cancer (PC). A retrospective chart review was performed for all (n = 82) PC patients referred for EUS-guided fiducial placement by a single endosonographer at a tertiary cancer center. Data regarding EUS-related technical details, SBRT characteristics, adverse events, and continuous visibility of fiducials were recorded and analyzed. Most patients included in the study had either locally advanced disease (32 patients, 39%) or borderline resectable disease (29 patients, 35%). Eighty-two PC patients underwent the placement of 230 fiducial markers under EUS guidance. The technical success rate of the fiducial placement was 98%. No immediate EUS-related adverse events were reported. The average time to the simulation C...
Source: Cancers - Category: Cancer & Oncology Authors: Tags: Article Source Type: research