Correlation between tumor invasion and somatostatin receptor subtypes in acromegaly

CONCLUSIONS: Tumor invasion is negatively correlated with SSTR2 level but is not associated with other SSTR subtypes. Patients with invasive tumors have a poorer response to SSA therapy, which may be due to the low level of SSTR2 expression. Therefore, SSTR2 could be considered as a routine investigative marker for aiding management of postoperative residual tumors.PMID:37856412 | DOI:10.3171/2023.7.JNS23858

Source: Journal of Neurosurgery - October 19, 2023 Category: Neurosurgery Authors: Shaolin Zhang Shun Yao Jinping Chen Farhana Akter Jia Yang Dimin Zhu Ailiang Zeng Wenli Chen Zhigang Mao Yonghong Zhu Haijun Wang Source Type: research