Exploring the Potential of Natural Products as Antiparasitic Agents for Neglected Tropical Diseases

Curr Top Med Chem. 2023 Oct 10. doi: 10.2174/0115680266256963230921061925. Online ahead of print.ABSTRACTRecent developments in the use of natural product-based molecules as antiparasitic agents for Malaria, leishmaniasis (LE), Chagas disease (CD), and Human African trypanosomiasis (HAT) are reviewed. The role of diverse plants in developing bioactive species is discussed in addition to analyzing the structural diversity of natural products as active agents and the diverse biological applications in CD, HAT, LE, and Malaria. This review focuses on medicinal chemistry, emphasizing the structural characteristics of natural molecules as bioactive agents against parasitic infections caused by Leishmania, Trypanosoma, and Plasmodium parasites.PMID:37842892 | DOI:10.2174/0115680266256963230921061925
Source: Current Topics in Medicinal Chemistry - Category: Chemistry Authors: Source Type: research