Regnase-1 downregulation promotes pancreatic cancer through myeloid-derived suppressor cell-mediated evasion of anticancer immunity

CONCLUSIONS: IL-1b-mediated Regnase-1 downregulation induces MDSCs and promotes pancreatic cancer through the evasion of anticancer immunity.PMID:37814340 | PMC:PMC10561497 | DOI:10.1186/s13046-023-02831-w

Source: Clin Med Res - October 9, 2023 Category: Research Authors: Junya Okabe Takahiro Kodama Yu Sato Satoshi Shigeno Takayuki Matsumae Kazuma Daiku Katsuhiko Sato Teppei Yoshioka Minoru Shigekawa Masaya Higashiguchi Shogo Kobayashi Hayato Hikita Tomohide Tatsumi Toru Okamoto Takashi Satoh Hidetoshi Eguchi Shizuo Akira Source Type: research