What is the natural history of TCFA “ Thin cap fibro atheroma ” ?

(Why should the number 65 bother us in TCFA-detected by OCT? Does this number really deserve that respect? Trying to find some truths from 8 questions with & without evidence.) 1. Does TCFA really make a plaque vulnerable? A.Yes B. No C. Maybe Answer: Yes & Maybe. But there seem to be more important factors other than TCFA for a plaque to become vulnerable making TCFA not really a big deal. 2. TCFP is more common in which lesions? A.Flow limiting lesion B.Nonflow limiting lesion C.No relationship between TCFA and flow Answer: No relation, rather a random relationship. 3. What is the natural history of TCFA? A.Get ruptured B.Static C.Get thickened D.Further thinning Answer: If someone can answer this query accurately, he can be rewarded Nobel Prize, in Lipidology There are some studies available though. Ref : This 2023 paper adds some anxious content to those who ignore TCFA. Long-term outcomes of patients with normal fractional flow reserve and thin-cap fibroatheroma EuroIntervention 2023;18:e1099-e1107. DOI: 10.4244/EIJ-D-22-00306  4. What to do with FFR-negative(FFR>.9), TCFA-positive lesions (tcfa<50mic)? Does stenting TCFA make it less vulnerable? No. Stents and scaffolds were never invented to make a plaque less vulnerable. 5. How is TCFA different in stable CAD from ACS situation? They are very different. In the ACS situation, TCFA (Whether the cap is intact or not ) needs imme...
Source: Dr.S.Venkatesan MD - Category: Cardiology Authors: Tags: Uncategorized Source Type: blogs