Anticoagulant in atrial fibrillation patients with prior intracranial haemorrhage: a meta-analysis

Conclusions For patients with AF with prior ICH, OAC is associated with a significant reduction in IS/SE and all-cause mortality without increasing ICH recurrence, but may increase major bleeding risk. Compared with warfarin, NOACs had a better safety profile and comparable efficacy. Further larger RCTs are warranted to validate these findings.
Source: Heart - Category: Cardiology Authors: Tags: Systematic review Source Type: research