Longitudinal Follow-Up of Children With HLHS and Association Between Norwood Shunt Type and Long-Term Outcomes: The SVRIII Study

CONCLUSIONS: By 12 years after the Norwood operation, shunt type has minimal association with RVEF, peak Vo2, complication rates, and transplant-free survival. RVEF is preserved among the subgroup of survivors who underwent CMR assessment. Low transplant-free survival, poor exercise performance, and accruing morbidities highlight the need for innovative strategies to improve long-term outcomes in patients with hypoplastic left heart syndrome.REGISTRATION: URL: https://www.CLINICALTRIALS: gov; Unique identifier: NCT00115934.PMID:37795623 | DOI:10.1161/CIRCULATIONAHA.123.065192

Source: Circulation - October 5, 2023 Category: Cardiology Authors: Caren S Goldberg Felicia Trachtenberg J William Gaynor William T Mahle Chitra Ravishankar Steven M Schwartz James F Cnota Richard G Ohye Russell Gongwer Michael Taylor Stephen Paridon Peter C Frommelt Katherine Afton Andrew M Atz Kristin M Burns Jon A Det Source Type: research