UArizona Cancer Center researchers discover iron-targeting approaches to halt proliferation of cancer cells

UArizona Cancer Center researchers discover iron-targeting approaches to halt proliferation of cancer cells
The new molecules exploit the iron dependency of malignant cells and could lead to the development of new anticancer drugs.
Lisa M. Dahm and Mark Anthony Febbo
Sept. 14, 2023
University of Arizona Cancer Centeryu-shiensong_elisatomat-web.jpg
Yu-Shien Sung (left), doctoral student in the Tomat Lab, and University of Arizona Cancer Center member Elisa Tomat, are studying an iron-targeting molecule that may lead to the development of new anticancer drugs.HealthScience and TechnologyAdaptationCancer CenterCollege of ScienceDeterminationTech Launch Arizona
Media contact(s)Mark Febbo
University of Arizona Cancer [e-mail]520-343-1289Researchers at theUniversity of Arizona Cancer Center discovered a new class of iron-targeting compounds that hamper the proliferation of cultured malignant cells in a laboratory setting. The results of the study were published in theJournal of the American Chemical Society." Cancer cells are what we call ' addicted ' to iron, and so we are making compounds that are able to interfere with the availability of iron in cancer cells, " saidElisa Tomat, professor in the Department of Chemistry and Biochemistry at theUArizona College of Science and member of the UArizona Cancer Center.The discovery could lead to the development of broad-spectrum, anticancer drugs that target iron metabolism.The team has been working withTec...

Source: The University of Arizona: Health - September 14, 2023 Category: Universities & Medical Training Authors: mittank Source Type: research