Consumption of cashew nut induced anxiolytic-like behavior in dyslipidemic rats consuming a high fat diet
This study aimed to evaluate the effect of cashew nut consumption on anxiety-like behavior in dyslipidemic rats. The groups formed were: Control (CONT), Dyslipidemic (DL) and Dyslipidemic cashew nuts (DLCN). Tests to assess anxiety parameters were performed after the treatment period. Brain fatty acid profiles were analyzed. The animals in the DLCN group showed more rearing than DL, without differing from the CONT and less grooming than either the DL and CONT in the Open Field. In the Elevated Plus Maze, DLCN spent more time on the open arms and in the central area compared to the other groups. As for brain fatty acids, there was a reduction in polyunsaturated fatty acids for the DLCN compared to the other groups. The cashew nut, rich in fatty acids, phenolic and flavonoid compounds, reduced the anxiogenic-like behavior caused by dyslipidemia in rats without altering brain fatty acids.PMID:37597587 | DOI:10.1016/j.bbr.2023.114634
Source: Behavioural Brain Research - Category: Neurology Authors: Celina de Castro Querino Dias Marta Suely Madruga Gabriel Henrique Oliveira Almeida Mar ília Ferreira Frazão Tavares de Melo Vanessa Bordin Viera Camila Carolina de Menezes Santos Bertozzo Larissa Maria Gomes Dutra Ana Paula Vilar Alves Francileide Amar Source Type: research