Altered Gene Expression of Cytochrome P450 and ABC Transporter in Human Hepatocellular Carcinoma HepG2 Cells Exposed to Bardoxolone Methyl

In conclusion, this study demonstrated that the gene expression
of several CYPs and ABC transporters in HepG2 cells was altered when exposed to
BX, suggesting the need to pay careful attention to drug-drug interactions in
patients receiving BX for CKD treatment. [...] Georg Thieme Verlag Rüdigerstraße 14, 70469 Stuttgart,
GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text

Source: Drug Research - August 17, 2023 Category: Drugs & Pharmacology Authors: Nagai, Katsuhito Fukuno, Shuhei Miura, Takeshi Yasuda-Imanishi, Eri Konishi, Hiroki Tags: Short Communication Source Type: research