The need to link anaphylaxis signs and symptoms with targeted therapeutic strategies

Anaphylaxis is challenging to diagnose and manage for patients, caregivers, and clinicians alike, largely because there is no reference standard diagnostic test. The diagnosis instead relies on a combination of signs and symptoms from up to 5 organ systems, including the mucosal/dermatologic, gastrointestinal, respiratory, cardiovascular, and neurologic systems.1,2 Guidelines emphasize epinephrine as the first-line anaphylaxis therapy, and repeat dosing or initiation of an epinephrine infusion is indicated for refractory cases.
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: Editorial Source Type: research