Sacubitril/valsartan effects on arrhythmias and left ventricular remodelling in heart failure: An observational study

CONCLUSION: Sacubitril/valsartan reduced the number of premature ventricular complexes and increased the percentage of biventricular pacing in a cohort of HFrEF patients already on optimal medical therapy. PVC reduction did not correlate with reverse left ventricular remodelling. Whether sacubitril/valsartan has any direct antiarrhythmic effects is an issue to be better explored in future studies.PMID:37467909 | DOI:10.1016/j.vph.2023.107196

Source: Vascular Pharmacology - July 19, 2023 Category: Drugs & Pharmacology Authors: Mauro Acquaro Laura Scelsi Beatrice Pasotti Alessandro Seganti Marcello Spolverini Alessandra Greco Sandra Schirinzi Annalisa Turco Antonio Sanzo Simone Savastano Roberto Rordorf Stefano Ghio Source Type: research