Statins for women with polycystic ovary syndrome not actively trying to conceive

CONCLUSIONS: The evidence for all main outcomes of this review was of very low certainty. Due to the limited evidence, we are uncertain if statins compared with placebo, or statins plus metformin compared with metformin alone, improve resumption of menstrual regularity. The trial evaluating statin plus OCP versus OCP alone reported neither of our primary outcomes. No other studies reported resumption of spontaneous ovulation. We are uncertain if statins improve hirsutism, acne severity, or testosterone. All trials that measured adverse events reported no significant differences between the groups.PMID:37462232 | PMC:PMC10353291 | DOI:10.1002/14651858.CD008565.pub3
Source: Cochrane Database of Systematic Reviews - Category: General Medicine Authors: Source Type: research