Neutrophil-to-Lymphocyte ratio and Monocyte-to-HDL ratio as a Biomarker of Urolithiasis

AbstractKidney stones are associated with increased chances of chronic kidney disorders, kidney failure, diabetes, hypertension, and cardiovascular disorders globally. This case –control study is designed to investigate the fluctuations in neutrophil-to-lymphocyte ratio (NLR) and monocyte-to-high-density lipid (HDL) ratio by comparing healthy subjects with cases suffering from kidney stones. Hematological and biochemical assays from 117 blood samples of cases and 117 cont rol, collected between October 2021 to June 2022, were inferred by applying statistical tests. Aftert-test, various hematological parameters of diseased and control samples showed significant differences which comprise hemoglobin, neutrophils, lymphocytes, NLR, eosinophils, MCV, MCHC, RBCs, WBCs, and monocytes. Our investigation gives evidence of the differentiation of kidney stone patients because of the CBC and lipid profile results. These results can be utilized as a promising indicator for the analysis of kidney stones.
Source: Comparative Clinical Pathology - Category: Pathology Source Type: research