Retroviral Activation as a Component of Neuronal Aging
In this study, we further found that treatment with abacavir can attenuate the augmented inflammation and protein aggregates in human neurons during prolonged culture and in the neurons of FL from aged mice, indicating ERV targeting as a promising strategy to delay brain aging and extend healthspan.
Link: https://doi.org/10.1016/j.celrep.2023.112593
Source: Fight Aging! - Category: Research Authors: Reason Tags: Daily News Source Type: blogs