CsHscB Derived from a Liver Fluke Clonorchis Sinensis Ameliorates Cholestatic Hepatic Fibrosis in a Mouse Model of Sclerosing Cholangitis

CONCLUSION: Overall, our data show that rCsHscB attenuates the progression of cholestatic fibrosis induced by DDC and supports the potential for manipulating the parasite-derived molecule to treat certain immune-mediated disorders.PMID:37076961 | DOI:10.2174/1566524023666230418111949

Source: Current Molecular Medicine - April 18, 2023 Category: Molecular Biology Authors: Qian Yu Stephane Koda Na Xu Jing Li Jian-Ling Wang Man Liu Ji-Xin Liu Yu Zhang Hui-Min Yang Bei-Bei Zhang Xiang-Yang Li Xiao-Cui Li Ren-Xian Tang Kui-Yang Zheng Chao Yan Source Type: research