Retrospective Pediatric Cohort Study Validates NEOS Score and Demonstrates Applicability in Children With Anti-NMDAR Encephalitis

Discussion Our data support the applicability of the NEOS score in children with NMDARE. Although not yet validated in prospective studies, NEOS also predicted cognitive impairment in our cohort. Consequently, the score could help identify patients at risk of poor overall clinical outcome and poor cognitive outcome and thus aid in selecting not only optimized initial therapies for these patients but also cognitive rehabilitation to improve long-term outcomes.

http://nn.neurology.org/cgi/content/short/10/3/e200102?rss=1

Source: Neurology Neuroimmunology and Neuroinflammation - March 22, 2023 Category: Neurology Authors: Nikolaus, M., Rausch, P., Rostasy, K., Bertolini, A., Wickström, R., Johannsen, J., Denecke, J., Breu, M., Schimmel, M., Diepold, K., Haeusler, M., Quade, A., Berger, A., Rosewich, H., Steen, C., von Au, K., Dreesmann, M., Finke, C., Bartels, F., Tags: Autoimmune diseases, Encephalitis, All Pediatric Research Article Source Type: research