Optimizing maximum resection of glioblastoma: Raman spectroscopy versus 5-aminolevulinic acid

CONCLUSIONS: According to the study data, RS is capable of detecting tumor-infiltrated brain with higher sensitivity but lower specificity than the current standard of 5-ALA. With further technological and workflow advancements, RS in combination with protoporphyrin IX fluorescence may contribute to pathology-tailored glioma resection in the future.PMID:36681953 | DOI:10.3171/2022.11.JNS22693

Source: Journal of Neurosurgery - January 22, 2023 Category: Neurosurgery Authors: Johannes Herta Anna Cho Thomas Roetzer-Pejrimovsky Romana H öftberger Wolfgang Marik Gernot Kronreif Tanja Peilnsteiner Karl R össler Stefan Wolfsberger Source Type: research