The sodium iodide symporter (NIS) as theranostic gene: potential role in pre-clinical therapy of extra-thyroidal malignancies
ConclusionNIS-mediated expression in combination with 131I can be considered a promising approach in the preclinical treatment of extra-thyroidal malignancies and metastases. Malignant cells expressing NIS are thought to accumulate radionuclides intracellularly, which contributes to the remarkable therapeutic effects observed.
Source: Clinical and Translational Imaging - Category: Radiology Source Type: research
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