Polymorphisms of the apolipoprotein E gene affect response to atorvastatin therapy in acute ischemic stroke
CONCLUSION: APOE gene polymorphisms affect the biological functions of atorvastatin. Compared to the ε3 or ε4 allele, the ε2 allele exerted a greater lipid-lowering effect on LDL-C levels, enhanced the ability of atorvastatin to stabilize carotid artery plaques, and slowed carotid artery plaque progression.PMID:36426228 | PMC:PMC9678920 | DOI:10.3389/fcvm.2022.1024014
Source: Atherosclerosis - Category: Cardiology Authors: QianQian Bi XiaoYu Zhou YanQin Lu Wang Fu YongPeng Wang Feng Wang Jue Wang Source Type: research
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