The Independent Associations of Anti-M üllerian Hormone and Estradiol Levels over the Menopause Transition with Lipids/lipoproteins: The Study of Women's Health Across the Nation

The menopause transition (MT) is a critical stage for cardiovascular disease (CVD) risk acceleration. 1 As women traverse the MT, they experience a reduction in ovarian reserve and adverse changes in multiple CVD risk factors such as lipids and lipoproteins. Within 1 year of the final menstrual period (FMP), low density lipoprotein-cholesterol (LDL-C) and apolipoprotein B (apo B) rise sharply. 2,3 This non-linear association between lipids/lipoproteins and time relative to FMP supports a critical contribution of ovarian aging to pro-atherogenic lipid/lipoprotein changes during the MT.

Source: Journal of Clinical Lipidology - November 21, 2022 Category: Lipidology Authors: Samar R. El Khoudary, Xirun Chen, Meiyuzhen Qi, Carol A. Derby, Maria M. Brooks, Rebecca C. Thurston, Imke Janssen, Sybil Crawford, Jennifer S. Lee, Elizabeth A. Jackson, Claudia U. Chae, Daniel McConnell, Karen A. Matthews Tags: Original Research Source Type: research