Systemic gene transfer enables optogenetic pacing of mouse hearts

Conclusions
Gene transfer generates sufficient ChR2 photocurrent for reliable optogenetic pacing in vivo and lays out the basis for future optogenetic pacemaker and pain-free defibrillation therapies.

Source: Cardiovascular Research - April 16, 2015 Category: Cardiology Authors: Vogt, C. C., Bruegmann, T., Malan, D., Ottersbach, A., Roell, W., Fleischmann, B. K., Sasse, P. Tags: Ion channels and arrhythmias Source Type: research