Network pharmacology approach to investigate the multitarget mechanisms of Zhishi Rhubarb Soup on acute cerebral infarction

CONCLUSIONS: This study demonstrated that ZRS improved cerebral ischaemic injury by inhibiting neuroinflammation partly via the AGE-RAGE signalling pathway. It provides a theoretical basis for the clinical application of ZRS in the treatment of ACI.PMID:35938510 | DOI:10.1080/13880209.2022.2103718

Source: Pharmaceutical Biology - August 8, 2022 Category: Drugs & Pharmacology Authors: Yuejia Shao Yue Zhang Rongrong Wu Lurui Dou Fengjiao Cao Yuqing Yan Yuming Tang Chi Huang Yang Zhao Jinghua Zhang Source Type: research