Intestine epithelial cell-derived extracellular vesicles alleviate inflammation induced by Clostridioides difficile TcdB through the activity of TGF- β1

ConclusionFor the first time, our study demonstrated that I-Evs originated from intestine epithelial cells can alleviate inflammation induced byC. difficile TcdB both in vitro and in vivo. Therefore, I-Evs might be potentially a novel endogenous candidate for effective treatment of CDI.

Source: Molecular and Cellular Toxicology - July 30, 2022 Category: Cytology Source Type: research