Low-dose nifedipine rescues impaired endothelial progenitor cell-mediated angiogenesis in diabetic mice

In conclusion, low-dose nifedipine can enhance EPCs' angiogenic potential and protect against cerebral ischemic injury in diabetic mice. It is implied that chronic treatment with low-dose nifedipine may be a safe and economic manner to prevent ischemic diseases (including stroke) in diabetes.PMID:35882957 | DOI:10.1038/s41401-022-00948-w

Source: Acta Pharmacologica Sinica - July 26, 2022 Category: Drugs & Pharmacology Authors: Cheng Peng Li-Jun Yang Chuan Zhang Yu Jiang Liu-Wen-Xin Shang Jia-Bei He Zhen-Wei Zhou Xia Tao Lu Tie Alex F Chen He-Hui Xie Source Type: research