Immune and Genetic Signatures of Breast Carcinomas Triggering Anti-Yo-Associated Paraneoplastic Cerebellar Degeneration

Discussion
These data confirm the role of genetic alterations of Yo antigens in triggering the immune tolerance breakdown but also outline a specific biomolecular profile in Yo-PCD BCs, suggesting a cancer-specific pathogenesis.

Source: Neurology Neuroimmunology and Neuroinflammation - July 12, 2022 Category: Neurology Authors: Peter, E., Treilleux, I., Wucher, V., Jougla, E., Vogrig, A., Pissaloux, D., Paindavoine, S., Berthet, J., Picard, G., Rogemond, V., Villard, M., Vincent, C., Tonon, L., Viari, A., Honnorat, J., Dubois, B., Desestret, V. Tags: Research Article Source Type: research