The association between mitochondrial DNA abundance and stroke: A combination of multivariable-adjusted survival and Mendelian randomization analyses

CONCLUSIONS: Although the results from both multivariable-adjusted prospective and basis MR analyses did not show an association between low mtDNA and increased risk of ischemic stroke, in-depth MR sensitivity analyses may suggest evidence for a causal relationship.PMID:35793595 | DOI:10.1016/j.atherosclerosis.2022.06.1012

Source: Atherosclerosis - July 6, 2022 Category: Cardiology Authors: Leon G Martens Jiao Luo Marieke J H Wermer Ko Willems van Dijk Sara H ägg Felix Grassmann Raymond Noordam Diana van Heemst Source Type: research