The effect of chronic exposure to metformin in a new type-2 diabetic NONcNZO10/LtJ mouse model of stroke

CONCLUSION: The study suggests that the prolonged effect of metformin-induced euglycemia promoted the microglial activation, reduced neuronal cell death, and improved the overall survival following stroke, without any change in infarct size.PMID:35792967 | DOI:10.1007/s43440-022-00382-z

Source: Pharmacological Reports - July 6, 2022 Category: Drugs & Pharmacology Authors: Rashmi Kumari Lisa Willing Scot R Kimball Ian A Simpson Source Type: research