Neurologic Complications of Osler-Weber-Rendu Syndrome: A Case Report and Literature Review (P3.058)

CONCLUSIONS: Brain abscess or ischemic stroke must be expected in patients with history of OWRS who present with neurologic manifestations. Family members of such patients should be screened for OWRS with appropriate genetic testing. All the patients with OWRS, whether symptomatic or not, should be screened for pulmonary AVMs. If found, pulmonary AVM’s should be treated to prevent paradoxical embolism which can result in brain abscess or ischemic stroke, both of which can be potentially fatal. Endovascular embolization is the treatment of choice for pulmonary AVMS and a long term follow-up is recommended after the procedure to prevent any complications. Those patients treated for pulmonary AVMs, likely should be screened for recanalization with a pulmonary angiogram at routine intervals, suggested to be every 10 years. Our case illustrates that CT angiogram can be insufficient for this task. Study Supported by: SelfDisclosure: Dr. Farooq has nothing to disclose. Dr. Mowla has nothing to disclose. Dr. AbdelRazek has nothing to disclose. Dr. Iqbal has nothing to disclose. Dr. Sawyer has nothing to disclose.
Source: Neurology - Category: Neurology Authors: Tags: Headache II Source Type: research