Acute ischemic stroke due to Left Ventricular Noncompaction Syndrome from a novel mutation of the Lamin A/C gene (P2.254)

Conclusion: LVNC is a risk factor for cardioembolic ischemic stroke particularly in young patients that is not well known. Patients with suspected LVNC by echocardiography should undergo cardiac MRI for confirmation and genetic testing in particular for mutations in the LMNA gene. The prognosis of those with LVNC syndrome is poor; most worsen over time and need ultimately transplantation. Close follow-up is required.Disclosure: Dr. Vongveeranonchai has nothing to disclose. Dr. Mittal has nothing to disclose. Dr. Ramos Estebanez has nothing to disclose. Dr. DeGeorgia has received personal compensation for activities with OSRAM Medical Incorporated as a consultant.

Source: Neurology - April 8, 2015 Category: Neurology Authors: Vongveeranonchai, N., Mittal, S., Ramos Estebanez, C., De Georgia, M. Tags: Cerebrovascular Disease and Interventional Neurology: Genetics and Stroke Source Type: research