Autoimmune Cerebellar Ataxia: Treatment Responses and Outcomes in 118 Patients (I4-4B)

CONCLUSION: The autoantibody profile of autoimmune cerebellar ataxias is diverse. Though usually severe, improvements may occur, particularly in patients with non-paraneoplastic disorders and in those harboring autoantibodies directed against neural plasma membrane protein antigens.Disclosure: Dr. Jones has nothing to disclose. Dr. Pittock's institution has received compensation for activities with Alexion Pharmaceuticals, Medimmune, and Chugai Pharma. Dr. Pittock and his institution stand to receive royalty payments in the technology entitled "Neuromyelitis Optica Autoantibodie Dr. Lennon stands to receive royalty payments for commercial assays to detect of Aquaporin 4-specific Autoantibody. Dr. Eggers has nothing to disclose. Dr. Ahlskog has nothing to disclose. Research support from MedImmune for a laboratory diagnostics study.

Source: Neurology - April 8, 2015 Category: Neurology Authors: Jones, A., Pittock, S., Lennon, V., Eggers, S., Ahlskog, J., McKeon, A. Tags: Infectious, Paraneoplastic, and Autoimmune Encephalopathies: Advances in Clinical Diagnosis and Emerging Insights about Pathogenesis Data Blitz Presentations Source Type: research