World Journal of Gastroenterology : WJG This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Computed tomography-based radiomics to predict early recurrence of hepatocellular carcinoma post-hepatectomy in patients background on cirrhosis
CONCLUSION: The combined model, integrating both radiomics and clinical-radiologic characteristics, exhibited excellent performance in HCC with cirrhosis. The K-M curves assessing OS revealed statistically significant differences.PMID:38681988 | PMC:PMC11045480 | DOI:10.3748/wjg.v30.i15.2128 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - April 29, 2024 Category: Gastroenterology Authors: Gui-Xiang Qian Zi-Ling Xu Yong-Hai Li Jian-Lin Lu Xiang-Yi Bu Ming-Tong Wei Wei-Dong Jia Source Type: research

Interplay between metabolic dysfunction-associated fatty liver disease and renal function: An intriguing pediatric perspective
World J Gastroenterol. 2024 Apr 21;30(15):2081-2086. doi: 10.3748/wjg.v30.i15.2081.ABSTRACTOver recent years, the nomenclature of non-alcoholic fatty liver disease has undergone significant changes. Indeed, in 2020, an expert consensus panel proposed the term "Metabolic (dysfunction) associated fatty liver disease" (MAFLD) to underscore the close association of fatty liver with metabolic abnormalities, thereby highlighting the cardiometabolic risks (such as metabolic syndrome, type 2 diabetes, insulin resistance, and cardiovascular disease) faced by these patients since childhood. More recently, this term has been further ...
Source: World Journal of Gastroenterology : WJG - April 29, 2024 Category: Gastroenterology Authors: Michele Nardolillo Fabiola Rescigno Mario Bartiromo Dario Piatto Stefano Guarino Pierluigi Marzuillo Emanuele Miraglia Del Giudice Anna Di Sessa Source Type: research

Taurine attenuates activation of hepatic stellate cells by inhibiting autophagy and inducing ferroptosis
CONCLUSION: Taurine exerts therapeutic effects on liver fibrosis via mechanisms that involve inhibition of autophagy and trigger of ferroptosis and ferritinophagy in HSCs to eliminate aHSCs.PMID:38681990 | PMC:PMC11045481 | DOI:10.3748/wjg.v30.i15.2143 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - April 29, 2024 Category: Gastroenterology Authors: Sen Li Qian-Jun Ren Can-Hao Xie Yang Cui Li-Tao Xu Yi-Dan Wang Su Li Xing-Qiu Liang Bin Wen Ming-Kun Liang Xiao-Fang Zhao Source Type: research

OSW-1 triggers necroptosis in colorectal cancer cells through the RIPK1/RIPK3/MLKL signaling pathway facilitated by the RIPK1-p62/SQSTM1 complex
CONCLUSION: We propose that OSW-1 can induce necroptosis through the RIPK1/RIPK3/MLKL signaling pathway, and that this effect is mediated by the RIPK1-p62/SQSTM1 complex, in CRC cells. These results provide a theoretical foundation for the use of OSW-1 in the clinical treatment of CRC.PMID:38681991 | PMC:PMC11045482 | DOI:10.3748/wjg.v30.i15.2155 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - April 29, 2024 Category: Gastroenterology Authors: Nan Wang Chao-Yang Li Teng-Fei Yao Xiao-Dan Kang Hui-Shu Guo Source Type: research

Hepatocellular carcinoma and musculoskeletal system: A narrative literature review
World J Gastroenterol. 2024 Apr 21;30(15):2109-2117. doi: 10.3748/wjg.v30.i15.2109.ABSTRACTMusculoskeletal alterations in hepatocellular carcinoma (HCC) are less common than liver-related complications. However, they can significantly impact the quality of life and overall prognosis of patients with HCC. The main obstacle in the clinical assessment of HCC-induced musculoskeletal alterations is related to effective and timely diagnosis because these complications are often asymptomatic and unapparent during routine clinical evaluations. This narrative literature review aimed to provide a comprehensive overview of the contem...
Source: World Journal of Gastroenterology : WJG - April 29, 2024 Category: Gastroenterology Authors: Jelena Jadzic Danijela Djonic Source Type: research

Necroptosis contributes to non-alcoholic fatty liver disease pathoetiology with promising diagnostic and therapeutic functions
World J Gastroenterol. 2024 Apr 14;30(14):1968-1981. doi: 10.3748/wjg.v30.i14.1968.ABSTRACTNonalcoholic fatty liver disease (NAFLD) is the most prevalent type of chronic liver disease. However, the disease is underappreciated as a remarkable chronic disorder as there are rare managing strategies. Several studies have focused on determining NAFLD-caused hepatocyte death to elucidate the disease pathoetiology and suggest functional therapeutic and diagnostic options. Pyroptosis, ferroptosis, and necroptosis are the main subtypes of non-apoptotic regulated cell deaths (RCDs), each of which represents particular characteristic...
Source: World Journal of Gastroenterology : WJG - April 29, 2024 Category: Gastroenterology Authors: Hong-Ju Sun Bo Jiao Yan Wang Yue-Hua Zhang Ge Chen Zi-Xuan Wang Hong Zhao Qing Xie Xiao-Hua Song Source Type: research

Topic highlight on texture and color enhancement imaging in gastrointestinal diseases
In conclusion, TXI can improve gastrointestinal lesion detection and qualitative diagnosis. Therefore, further studies on the efficacy of TXI in clinical practice are required.PMID:38681121 | PMC:PMC11045492 | DOI:10.3748/wjg.v30.i14.1934 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - April 29, 2024 Category: Gastroenterology Authors: Osamu Toyoshima Toshihiro Nishizawa Keisuke Hata Source Type: research

Preoperative albumin-bilirubin score and liver resection percentage determine postoperative liver regeneration after partial hepatectomy
CONCLUSION: Liver regeneration posthepatectomy was determined by the resection percentage and preoperative ALBI score. This knowledge helps surgeons decide the timing and type of rehepatectomy for recurrent cases.PMID:38681122 | PMC:PMC11045494 | DOI:10.3748/wjg.v30.i14.2006 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - April 29, 2024 Category: Gastroenterology Authors: Kazuhiro Takahashi Masahiko Gosho Yoshihiro Miyazaki Hiromitsu Nakahashi Osamu Shimomura Kinji Furuya Manami Doi Yohei Owada Koichi Ogawa Yusuke Ohara Yoshimasa Akashi Tsuyoshi Enomoto Shinji Hashimoto Tatsuya Oda Source Type: research

Current status of liver transplantation for human immunodeficiency virus-infected patients in mainland China
This study provides an overview of the current landscape of HIV-positive patients receiving liver transplantation (LT) in mainland China. To date, our transplant center has conducted LT for eight end-stage liver disease patients co-infected with HIV, and all but one, who died two months postoperatively due to sepsis and progressive multi-organ failure, have survived. Comparative analysis with hepatitis B virus-infected patients during the same period revealed no statistically significant differences in acute rejection reactions, cytomegalovirus infection, bacteremia, pulmonary infections, acute kidney injury, new-onset can...
Source: World Journal of Gastroenterology : WJG - April 29, 2024 Category: Gastroenterology Authors: Jian-Xin Tang Dong Zhao Source Type: research

Bowel function and inflammation: Is motility the other side of the coin?
World J Gastroenterol. 2024 Apr 14;30(14):1963-1967. doi: 10.3748/wjg.v30.i14.1963.ABSTRACTDigestion and intestinal absorption allow the body to sustain itself and are the emblematic functions of the bowel. On the flip side, functions also arise from its role as an interface with the environment. Indeed, the gut houses microorganisms, collectively known as the gut microbiota, which interact with the host, and is the site of complex immune activities. Its role in human pathology is complex and scientific evidence is progressively elucidating the functions of the gut, especially regarding the pathogenesis of chronic intestin...
Source: World Journal of Gastroenterology : WJG - April 29, 2024 Category: Gastroenterology Authors: Alba Panarese Source Type: research

< em > Fusobacterium nucleatum < /em > -induced imbalance in microbiome-derived butyric acid levels promotes the occurrence and development of colorectal cancer
CONCLUSION: F. nucleatum can promote cancer progression through its inhibitory effect on butyric acid, via the AMPK signaling pathway.PMID:38681125 | PMC:PMC11045493 | DOI:10.3748/wjg.v30.i14.2018 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - April 29, 2024 Category: Gastroenterology Authors: Qi-Long Wu Xiao-Ting Fang Xin-Xin Wan Qing-Yong Ding Yan-Jun Zhang Ling Ji Yong-Liang Lou Xiang Li Source Type: research

Immune checkpoint inhibitor-associated gastritis: Patterns and management
World J Gastroenterol. 2024 Apr 14;30(14):1941-1948. doi: 10.3748/wjg.v30.i14.1941.ABSTRACTImmune checkpoint inhibitors (ICIs) are widely used due to their effectiveness in treating various tumors. Immune-related adverse events (irAEs) are defined as adverse effects resulting from ICI treatment. Gastrointestinal irAEs are a common type of irAEs characterized by intestinal side effects, such as diarrhea and colitis, which may lead to the cessation of ICIs. Although irAE gastritis is rarely reported, it may lead to serious complications such as gastrorrhagia. Furthermore, irAE gastritis is often difficult to identify early d...
Source: World Journal of Gastroenterology : WJG - April 29, 2024 Category: Gastroenterology Authors: Jing Lin Zhong-Qiao Lin Shi-Cheng Zheng Yu Chen Source Type: research

Liver biopsy in the post-hepatitis C virus era in Japan
In conclusion, pathologists should be attuned to the changing landscape of liver diseases and approach liver biopsies with care and attention to detail.PMID:38681127 | PMC:PMC11045496 | DOI:10.3748/wjg.v30.i14.1949 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - April 29, 2024 Category: Gastroenterology Authors: Yoshihiro Ikura Takako Okubo Yasuhiro Sakai Source Type: research

Outcomes of endoscopic sclerotherapy for jejunal varices at the site of choledochojejunostomy (with video): Three case reports
CONCLUSION: We conclude that endoscopic sclerotherapy with lauromacrogol/α-butyl cyanoacrylate injection can be an easy, effective, safe and low-cost treatment option for jejunal varicose bleeding at the site of choledochojejunostomy.PMID:38681128 | PMC:PMC11045488 | DOI:10.3748/wjg.v30.i14.2059 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - April 29, 2024 Category: Gastroenterology Authors: Jun Liu Peng Wang Li-Mei Wang Jing Guo Ning Zhong Source Type: research

Characteristics of early gastric tumors with different differentiation and predictors of long-term outcomes after endoscopic submucosal dissection
CONCLUSION: Differentiations of gastric mucosal tumors have different epidemiological and endoscopic characteristics, which are closely related to the safety and efficacy of ESD.PMID:38681129 | PMC:PMC11045489 | DOI:10.3748/wjg.v30.i14.1990 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - April 29, 2024 Category: Gastroenterology Authors: Hong-Yi Zhu Jie Wu Yuan-Miao Zhang Fang-Lan Li Jin Yang Bin Qin Jiong Jiang Ning Zhu Meng-Yao Chen Bai-Cang Zou Source Type: research