Clinical outcomes associated with neoadjuvant therapy for the treatment of resectable non ‐small cell lung cancer in real‐world practice
ConclusionsNeoadjuvant treatment with a combination of immunotherapy plus chemotherapy appears to achieve higher radiological and pathological responses than monotherapy for IIA-IIIB NSCLC. Log-rank analysis showed that a better outcome could be expected in patients with the addition of immunotherapy to neoadjuvant chemotherapy if compared with patients with chemotherapy alone in terms of DFS. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - May 2, 2024 Category: Respiratory Medicine Authors: Xiaojie Huang,
Guanchao Pang,
Zhirong Mao,
Baizhou Li,
Zhihua Teng,
Yan Yang,
Zijian Qiu,
Xiuxiu Chen,
Pingli Wang Tags: ORIGINAL ARTICLE Source Type: research
Analysis of the epidemiological situation of influenza in Guangzhou under the prevention and control of COVID ‐19 in June 2022
ConclusionA high proportion of adolescents and adults has respiratory pathogens detected during fever illnesses during June in 2022 under the prevention and control of COVID-19. These data indicate that diagnosis, prevention, and control of respiratory tract infection should be paid attention under the prevention and control of COVID-19. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - May 2, 2024 Category: Respiratory Medicine Authors: Yuezhi Deng,
Yongping Lin,
Weihong Lin Tags: ORIGINAL ARTICLE Source Type: research
Implications of intestinal microecology and immune function alterations for immunotherapy outcomes in advanced unresectable lung adenocarcinoma
ConclusionThe structuring of gut flora plays a pivotal role in augmenting the efficacy of anti-tumor immunotherapy, underscoring the interplay between intestinal microecology and immune response in cancer treatment outcomes. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - April 30, 2024 Category: Respiratory Medicine Authors: Shuang He,
Jin Tian,
Jianhua Zang,
Lin Long,
Peng Liu,
Yexi Zhang,
Jun Xiao Tags: ORIGINAL ARTICLE Source Type: research
Prognostic utility of blood inflammation biomarkers before and after treatment on the survival of patients with locally advanced non ‐small cell lung cancer undergoing stereotactic body radiotherapy
ConclusionsPost-SBRT PLR > 382.0 correlated with survival in patients undergoing SBRT. The decision tree model might play a role in future risk stratification to guide the clinical practice of individualized SBRT for LA-NSCLC. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - April 30, 2024 Category: Respiratory Medicine Authors: Fang Fang,
Zhen Jia,
Hongliang Xie,
Yangsen Cao,
Xiaofei Zhu,
Xiao Yu Yang,
Xueling Guo,
Huojun Zhang Tags: ORIGINAL ARTICLE Source Type: research
Clinical characteristics of persistent or recurrent pneumonia combined with airway malacia in children
ConclusionSevere airway malacia likely aggravates conditions combined with pneumonia. The proportion of multisite malacia was greater in severe airway malacia patients. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - April 30, 2024 Category: Respiratory Medicine Authors: Zhuxia Li,
Xinxing Zhang,
Huiquan Sun,
Chuangli Hao,
Xuejun Shao,
Jun Xu,
Xin Zhang,
Yuqing Wang Tags: ORIGINAL ARTICLE Source Type: research
Diagnostic outcomes of radial endobronchial ultrasound bronchoscopy guided by manual navigation in the evaluation of peripheral pulmonary lesions: An observational study
ConclusionsMN-guided r-EBUS is feasible in diagnosing PPLs, especially for lesions with bronchus sign on CT. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - April 30, 2024 Category: Respiratory Medicine Authors: Mingli Yuan,
Yi Hu,
Liangchao Wang,
Wen Yin,
Yang Xiao Tags: ORIGINAL ARTICLE Source Type: research
Causal influence of gut microbiota on small cell lung cancer: a Mendelian randomization study
ConclusionWe identified potential causal relationships between certain gut microbiota and SCLC, offering new insights into microbiome-mediated mechanisms of SCLC pathogenesis, resistance, mutations, and more. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - April 30, 2024 Category: Respiratory Medicine Authors: Wenjing Yang,
Xinxia Fan,
Wangshu Li,
Yan Chen Tags: ORIGINAL ARTICLE Source Type: research
Issue Information
No abstract is available for this article. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - April 30, 2024 Category: Respiratory Medicine Tags: ISSUE INFORMATION Source Type: research
Studying of anti ‐inflammatory and antioxidant effects of tectorigenin in ovalbumin‐induced asthma mice models
ConclusionTectorigenin could control inflammation and the secretion of inflammatory mediators of asthma, so it can be regarded as a potential antiasthma treatment with the ability to control eosinophilia-related problems. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - April 26, 2024 Category: Respiratory Medicine Authors: Jingning Guo,
Yanping Shi,
Yujun Wang,
Seyyed Shamsadin Athari,
Tao Chen Tags: ORIGINAL ARTICLE Source Type: research
Comparative study of imaging and pathology of primary mucinous adenocarcinoma with different imaging manifestations
ConclusionThe different imaging manifestations of mucinous adenocarcinoma are possibly due to the different amounts or viscosity of mucus produced, and the mechanisms of its formation may include (1) tumour cells in different shapes have different abilities to produce mucus; (2) tumours in different stages produce different amounts or viscosity of mucus; and (3) the TTF-1 and ALK genes affect the production of mucus. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - April 15, 2024 Category: Respiratory Medicine Authors: Jun Han,
Jie Gao,
Demei Chen,
Mou Du,
Yuxin Wu,
Xidong Ma,
Mei Xie,
Hua Han,
Chongchong Wu,
Xinying Xue Tags: ORIGINAL ARTICLE Source Type: research
Prognostic factors and predictive models for patients with lung large cell neuroendocrine carcinoma: Based on SEER database
ConclusionsThe nomogram obtained from our study is expected to be a useful tool for personalized prognostic prediction of LCNEC patients, which may help in clinical decision-making. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - April 13, 2024 Category: Respiratory Medicine Authors: Wenqiang Li,
Qian Huang,
Xiaoyu He,
Qian He,
Qun Lai,
Quan Yuan,
Zhiping Deng Tags: ORIGINAL ARTICLE Source Type: research
The impact of EGFR T790M mutation status following the development of Osimertinib resistance on the efficacy of Osimertinib in non ‐small cell lung cancer: A meta‐analysis
ConclusionsPersistence of the T790M gene mutation after the development of Osimertinib resistance is associated with higher therapeutic benefits of Osimertinib in NSCLC patients. The results of tissue detection are more significant than those of plasma detection. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - April 8, 2024 Category: Respiratory Medicine Authors: Liuxian Guo,
Guojin Zhou,
Min Huang,
Kejing Tang,
Jing Xu,
Jie Chen Tags: REVIEW ARTICLE Source Type: research
Efficacy of immune checkpoint inhibitors in advanced non ‐small cell lung cancer patients with KRAS mutations: A network meta‐analysis
ConclusionOur analysis found that among advanced NSCLC patients withKRAS gene mutations, first-line treatment with pembrolizumab alone demonstrated greater efficacy. Similarly, second-line treatment with nivolumab alone was found to be more effective in this patient population. However, the sample size of this study was limited, Therefore, additional clinical data is necessary to validate this finding in subsequent research. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - April 3, 2024 Category: Respiratory Medicine Authors: Lin Zhang,
Wei Chen,
Hongtao Wei,
Junxian Yu Tags: ORIGINAL ARTICLE Source Type: research
Issue Information
No abstract is available for this article. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - April 3, 2024 Category: Respiratory Medicine Tags: ISSUE INFORMATION Source Type: research
Radiological and clinical features of large consolidative ‐type pulmonary invasive mucinous adenocarcinoma
ConclusionHalo, vacuole, angiogram, and dead branch signs were frequently observed in consolidative-type IMA. Kirsten rat sarcoma viral oncogene mutations are common in consolidative-type IMA, especially site G12V, whereas epidermal growth factor receptor mutations were rare; therefore, gene immunotherapy was more difficult. Most patients were in stage T3 –T4; however, lymph node metastasis was rare. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - March 27, 2024 Category: Respiratory Medicine Authors: Jiaqi Chen,
Linlin Qi,
Jianwei Wang,
Liyan Xue,
Qi Xue,
Jia Jia,
Guochao Zhang,
Jianing Liu,
Fenglan Li,
Shulei Cui Tags: ORIGINAL ARTICLE Source Type: research
