Effect of beta-blockers and angiotensin receptor blockers in reducing the aortic growth rate in children with bicuspid aortic valve-related aortopathy
The aim of this study is to evaluate the effect of beta-blockers and angiotensin receptor blockers in reducing the aortic growth rate in children with bicuspid aortic valve (BAV)-related aortopathy and ascending phenotype. (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - May 5, 2024 Category: Cardiology Authors: Emanuele Monda, Antonella Boccia, Ippolita Altobelli, Alfredo Mauriello, Gianantonio De Michele, Sabrina Siniscalchi, Adelaide Fusco, Annapaola Cirillo, Marta Rubino, Federica Verrillo, Gaetano Diana, Chiara Cirillo, Martina Caiazza, Eduardo Bossone, Ales Source Type: research

Association of echocardiographic parameters with all-cause and cardiovascular mortality in patients with type 2 diabetes
This study aimed to evaluate associations between echocardiography markers and mortality in patients with type 2 diabetes mellitus (T2DM). (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - May 5, 2024 Category: Cardiology Authors: Cheng-Chieh Lin, Chia-Ing Li, Chiu-Shong Liu, Chih-Hsueh Lin, Shing-Yu Yang, Tsai-Chung Li Source Type: research

Survival analysis and gender differences in hypertrophic cardiomyopathy proband patients referred for genetic testing11All authors contributed to this manuscript.
Hypertrophic cardiomyopathy (HCM) is believed to have low overall mortality rate, that could be influenced by gender, particularly among probands. We aimed to evaluate the survival rates and possible gender differences in a homogeneous cohort of HCM proband patients, referred for genetic testing, from the same geographical area, without differences in medical care access nor clinical referral pathways. (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - May 4, 2024 Category: Cardiology Authors: Rebeca Lorca, Mar ía Salgado, Rut Álvarez-Velasco, Julián R. Reguro, Vanesa Alonso, Juan Gómez, Eliecer Coto, Elías Cuesta-Llavona, Eva Lopez-Negrete, Isaac Pascual, Pablo Avanzas, Maite Tome Source Type: research

Inflammation in heart failure with preserved ejection fraction: A bystander or a participant?
We read a paper by Ferreira et al. on the correlation between high-sensitivity C-reactive protein (hsCRP) and heart failure with preserved ejection fraction (HFpEF) with great interest [1]. Managing HFpEF remains challenging, as no single medication has demonstrated significant improvements in patient outcomes. Ferreira et al.'s study revealed that elevated hs-CRP levels in HFpEF patients are linked to adverse outcomes, including a higher risk of heart failure events and mortality, suggesting inflammation's critical role in HFpEF. (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - May 4, 2024 Category: Cardiology Authors: Min Zhong, Xiaomin Yan Source Type: research

“Interstitial fibrosis is associated with left atrial remodeling and adverse clinical outcomes in selected low-risk patients with hypertrophic cardiomyopathy”
This study aimed to explore the interaction between interstitial fibrosis by ECV, LA morpho-functional parameters and adverse clinical outcomes in selected low-risk patients with HCM. (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - May 3, 2024 Category: Cardiology Authors: Lara Tondi, Silvia Pica, Gabriele Crimi, Giandomenico Disabato, Stefano Figliozzi, Antonia Camporeale, Andrea Bernardini, Luigi Tassetti, Valentina Milani, Massimo Francesco Piepoli, Massimo Lombardi Source Type: research

Acute effect of ultramarathon on systolic and diastolic cardiac function: Systematic review and meta-analysis
Ultramarathon running poses physiological challenges, impacting cardiac function. This systematic review and meta-analysis explore the acute effects of single-stage ultramarathon running on cardiac function. (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - May 3, 2024 Category: Cardiology Authors: Francisco Ver íssimo Perrout Lima, Diana de Medeiros Andrade, José Elias Filho, Pedro Lima Souza, Luciene Ferreira Azevedo, Marcelo Martins Coelho, Jorge Roberto Perrout de Lima, Patrícia Fernandes Trevizan, Mateus Camaroti Laterza, Daniel Godoy Martin Source Type: research

Critical aortic stenosis – The long-term burden
Decision-making about the optimal treatment strategy in newborns with critical aortic stenosis is still a challenge. Balloon valvuloplasty of the stenotic aortic valve or surgical valve reconstruction are the main treatment options, but also fetal aortic valvuloplasty is of increasing interest [1]. However, only few studies exist that paid attention to the longer-term outcome and these mainly focused on survival and reinterventions [2,3]. (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - May 3, 2024 Category: Cardiology Authors: Inga Voges, Jan Hinnerk Hansen Source Type: research

Temporal trend of first-line drug choice and treatment continuity for hypertension among citizens 75  years or over - a register-based, cohort study
Limited knowledge of antihypertensive treatment of the elderly potentially impedes effective strategies for hypertension management in this growing patient group. We aimed to investigate temporal trends for first-line drug choice for antihypertensive treatment and treatment continuity among patients ≥75 years from 2000 to 2021. (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - May 3, 2024 Category: Cardiology Authors: Sebastian K. Nielsen, Morten Lamberts, Nina Nouhravesh, Mads H. Jensen, Jarl E. Strange, Gunnar Gislason, Patricia Mcgettigan, Anders Holt Source Type: research

Negative selection bias for women inclusion in a clinical trial
Despite the growing awareness towards the importance of adequate representation of women in clinical trials among patients treated with percutaneous coronary intervention (PCI), available evidence continues to demonstrate a skewed distribution of study populations in favour of men. (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - May 3, 2024 Category: Cardiology Authors: Antonio Landi, Dik Heg, Enrico Frigoli, Helen Routledge, Fazila-Tun-Nesa Malik, Suzanne Pourbaix, Mirvat Alasnag, Pieter C. Smits, Marco Valgimigli Source Type: research

Specifics in the ECG diagnosis of takotsubo syndrome
I read with great interest the contribution of Looi et al. [1] about the electrocardiogram (ECG) changes in patients with the different phenotypic morphological variants of takotsubo syndrome (TTS); the authors TTS cohort included 168 patients with the apical TTS, and 26 with the non-apical TTS, which comprised of 11 patients with the mid-ventricular TTS, 5 patients with the basal TTS, and 10 patients with the focal TTS variants. The extent of T-wave inversion (TWI) (in terms of the number of ECG leads involved) was similar for both apical and non-apical groups on admission, but by day 1 the extent of TWI was greater in th...
Source: International Journal of Cardiology - May 3, 2024 Category: Cardiology Authors: John E. Madias Source Type: research

Quantifying myocardial active strain energy density: A comparative analysis of analytic and finite element methods for estimating left ventricular wall stress and strain
This study compared commonly used methods for calculating left ventricular wall stress with the finite element analysis and evaluated different approaches to strain estimation. We sought to improve the accuracy of contractance estimation by developing a novel stress equation. (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - May 2, 2024 Category: Cardiology Authors: David H. MacIver, Henggui Zhang Source Type: research

Deciphering mortality risk of diabetes medications in heart failure patients with diabetes mellitus under triple guideline-directed medical therapy
Scientific evidence regarding the impact of different combinations of diabetes medications in heart failure patients with diabetes mellitus (HFwDM) remains limited. (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - May 2, 2024 Category: Cardiology Authors: İnci Tuğçe Çöllüoğlu, Ahmet Çelik, Naim Ata, Dilek Ural, Anıl Şahin, Mustafa Mahir Ulgu, Emine Arzu Kanık, Şuayip Birinci, Mehmet Birhan Yılmaz Source Type: research

Digital health technologies in enhancing patient and caregiver engagement in heart failure management: Opportunities and challenges
The management of heart failure has undergone significant evolution, advancing from the initial utilization of digitalis and diuretics to the contemporary practice of personalized medicine and sophisticated device therapy. Despite these advancements, the persistent challenge of high hospitalization and readmission rates underscores an urgent need for innovative solutions. This manuscript explores how the integration of digital health technologies into interventional cardiology marks a paradigm shift in the management of heart failure. (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - May 2, 2024 Category: Cardiology Authors: Arif Albulushi, Dawoud I. Al Kindi, Nader Moawwad, Adel M. Kamel, Asif Khan, Mohamed A. Moustafa, Ahmed Al Kalbani Source Type: research

The H-index in the road for academic progression
The assessment of research quality and impact was historically challenging due to the limitations of existing metrics, the absence of standardized evaluation methodologies, and inadequate data accessibility. Traditional metrics like the number of publications, citations, or journal impact factors provided only a partial picture and didn't account for the actual influence of a researcher's work within their field. (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - May 2, 2024 Category: Cardiology Authors: Marco Zimarino, Umberto Benedetto, Francesco Pelliccia Source Type: research

Stroke risk after transcatheter aortic valve replacement in patients with carotid stenosis: A systematic review and meta-analysis
Stroke is a feared complication of transcatheter aortic valve replacement (TAVR). Patients undergoing TAVR typically have multiple comorbidities, such as carotid artery stenosis (CAS). We conducted the present meta-analysis to determine the risk of stroke and mortality following TAVR in patients with CAS. (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - May 1, 2024 Category: Cardiology Authors: Fernando Garagoli, Juan Guido Chiabrando, Ignacio Miguel Seropian, Marco Lombardi, Carla Romina Agatiello, Mar ía Luz Fernández Recalde, Rocco Vergallo, Italo Porto, Ignacio Martín Bluro Source Type: research