Omadacycline Noninferior to Moxifloxacin for Pneumonia
WEDNESDAY, Feb. 6, 2019 -- Omadacycline is noninferior to moxifloxacin for community-acquired bacterial pneumonia and noninferior to linezolid for acute bacterial skin infections, according to two studies published in the Feb. 7 issue of the New... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - February 6, 2019 Category: Pharmaceuticals Source Type: news

Auromedics Pharma LLC Issues Voluntary Nationwide Recall of Linezolid Injection 600mg/300ml, due to Presence White Particulate Matter that has been Identified as Mold
AuroMedics Pharma LLC is voluntarily recalling one lot of Linezolid Injection 600mg/300mL flexible bags, NDC 55150 -242 -51 batch CLZ160007 expiration August 2018 to the hospital level. This batch was distributed May 15 through August 14, 2017. The product was found to contain white particulate matter that has been identified as mold. This problem was discovered as a result of a product complaint in which the contents of one flexible bag from one batch CLZ160007 was found to contain white particulate matter. (Source: Food and Drug Administration)
Source: Food and Drug Administration - December 26, 2017 Category: Food Science Source Type: news

Linezolid Injection (New - Discontinuation)
Drug Shortage (Source: FDA Drug Shortages)
Source: FDA Drug Shortages - November 15, 2017 Category: Drugs & Pharmacology Source Type: news

Two antibiotics fight bacteria differently than thought
Two widely prescribed antibiotics — chloramphenicol and linezolid — may fight bacteria in a different way from what scientists and doctors thought for years, researchers have found. Instead of indiscriminately stopping protein synthesis, the drugs put the brakes on the protein synthesis machinery only at specific locations in th e gene. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - November 1, 2016 Category: Science Source Type: news

Two antibiotics fight bacteria differently than thought
(University of Illinois at Chicago) Two widely prescribed antibiotics -- chloramphenicol and linezolid -- may fight bacteria in a different way from what scientists and doctors thought for years, University of Illinois at Chicago researchers have found. Instead of indiscriminately stopping protein synthesis, the drugs put the brakes on the protein synthesis machinery only at specific locations in the gene. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 1, 2016 Category: Global & Universal Source Type: news

Zyvox (Linezolid) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - September 26, 2016 Category: Drugs & Pharmacology Source Type: news

Fentanyl can cause serotonin syndrome
3.5 out of 5 stars Serotonin Syndrome Induced by Fentanyl in a Child: Case Report. Robles LA. Clin Neuropharmacol 2015 Sept-Oct;38:206-8. Abstract When many clinicians think of serotonin syndrome (SS), they consider the usual suspects: Selective Serotonin Uptake Inhibitors (SSRIs) Citalopram Fluoxetine Sertraline Escitalopram Paroxetine Serotonin-Norepinephrine Reuptake Inhibitors Venlafaxine Duloxetine Antidepressants Trazodone Buspirone Clomipramine Aside from these common culprits, there are other commonly used drugs whose clear association with serotonin syndrome is less-often realized: Fentanyl Methadon...
Source: The Poison Review - July 8, 2016 Category: Toxicology Authors: Leon Gussow Tags: Medical fentanyl opioid serotonin syndrome Source Type: news

Comunicado de la FDA sobre la seguridad de los medicamentos: Reacciones graves en el sistema nervioso central (SNC) cuando se administra linezolid (Zyvox) a pacientes que toman ciertos medicamentos psiquiátricos
El 26 de julio de 2011, la Administración de Alimentos y Medicamentos de los EE.UU. (FDA) recibió informes sobre reacciones graves del sistema nervioso central (SNC) al administrarse el medicamento antibacterial linezolid (comercializado como Zyvox) a pacientes que toman ciertos medicamentos psiquiátricos que trabajan a través del sistema de serotonina del cerebro (medicamentos psiquiÃÆâ€â„...
Source: FDA Center for Drug Evaluation and Research - What's New - March 1, 2016 Category: Drugs & Pharmacology Source Type: news

South Africa: Miners and Inmates to Wait Up to Three Years for TB Meds
[DA] In a reply to DA parliamentary questions, the Minister of Health, Dr Aaron Motsoaledi, revealed that there is a significant need for the Linezolid drug to help in the treatment of Multi-drug resistant Tuberculosis (MDR-TB) and that the roll out of the medication to mines and prisons will only take place within the next two to three years. (Source: AllAfrica News: Tuberculosis)
Source: AllAfrica News: Tuberculosis - August 6, 2015 Category: Infectious Diseases Source Type: news

Teva Bolsters Injectable Portfolio With Launch Of Generic Lovenox And Generic Zyvox In The United States
Teva Pharmaceutical Industries Ltd., a leading global pharmaceutical company, recently announced the launch of the generic equivalent of Lovenox (enoxaparin sodium injection) in seven dosage strengths in the United States (Source: Pharmaceutical Online News)
Source: Pharmaceutical Online News - February 23, 2015 Category: Pharmaceuticals Source Type: news

Linezolid Susceptibility Results: A Surrogate for Tedizolid?Linezolid Susceptibility Results: A Surrogate for Tedizolid?
Tedizolid is an oxazolidinon antibacterial approved for some Gram-positive infections, but commercial susceptibility testing products are not yet available. Could linezolid be used as a surrogate? Annals of Clinical Microbiology and Antimicrobials (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - December 5, 2014 Category: Consumer Health News Tags: Pathology & Lab Medicine Journal Article Source Type: news

Omadacycline Noninferior to Moxifloxacin for Pneumonia
Second study shows noninferiority to linezolid for acute bacterial skin and skin - structure infections (Source: Pulmonary Medicine News - Doctors Lounge)
Source: Pulmonary Medicine News - Doctors Lounge - November 11, 2014 Category: Respiratory Medicine Tags: Infections, Pharmacy, Pulmonology, Journal, Source Type: news

Tedizolid: A New Oxazolidinone -- Shorter and Gentler?Tedizolid: A New Oxazolidinone -- Shorter and Gentler?
Paul G. Auwaerter, MD, offers his perspective on a new antibiotic for skin and soft tissue infections and why it might prove to have advantages over linezolid. Medscape Infectious Diseases (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - July 24, 2014 Category: Consumer Health News Tags: Infectious Diseases Commentary Source Type: news

South Africa: More MSF Patients With DR-TB Gain Access to Dramatically Cheaper Version of Life-Saving Drug
[MSF]After a three-year long struggle, Médecins Sans Frontières (MSF) has received approval from the South African Medicines Control Council (MCC) to import a dramatically more affordable version of an antibiotic, linezolid, in order to expand access to the medicine and provide better treatment options to patients with drug-resistant tuberculosis (DR-TB) in Khayelitsha, Western Cape. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - July 2, 2014 Category: African Health Source Type: news

South Africa: Litigation Threat May Prompt Access to Cheaper DR-TB Drug
[Health-e]South Africa may finally allow access to a cheaper form of the drug-resistant tuberculosis (DR-TB) drug linezolid following the lodging of a high court case. (Source: AllAfrica News: Tuberculosis)
Source: AllAfrica News: Tuberculosis - June 13, 2014 Category: Infectious Diseases Source Type: news