The TIRS trial: protocol for a cluster randomized controlled trial assessing the efficacy of preventive targeted indoor residual spraying to reduce Aedes -borne viral illnesses in Merida, Mexico
DiscussionThe findings from this study will provide robust epidemiological evidence of the efficacy of TIRS in reducing ABV illness and infection. If efficacious, TIRS could drive a paradigm shift inAedes control by consideringAe. aegypti behavior to guide residual insecticide applications and changing deployment to preemptive control (rather than in response to symptomatic cases), two major enhancements to existing practice.Trial registrationClinicalTrials.govNCT04343521. Registered on 13 April 2020. The protocol also complies with the WHO International Clinical Trials Registry Platform (ICTRP) (Additional file 1).Primary...
Source: Trials - October 8, 2020 Category: Research Source Type: clinical trials
Research Study to Assess New Chikungunya and Zika Vaccines in Healthy Adults in Mexico.
Conditions: Chikungunya; Zika Interventions: Biological: CHIK low dose; Biological: CHIK mid dose; Biological: CHIK high dose; Biological: ZIKA low dose; Biological: ZIKA mid dose; Biological: ZIKA high dose; Biological: Saline placebo Sponsor: University of Oxford Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 22, 2020 Category: Research Source Type: clinical trials
Investigating the Sylvatic Transmission and Reservoir Potential of Zika, Dengue, and Chikungunya Viruses of Co-located Humans and Long-tailed Macaques of Thailand and Cambodia
Conditions: Dengue Fever; Zika; Vector-Borne Diseases; Chikungunya Intervention: Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 17, 2020 Category: Research Source Type: clinical trials
