Sylvatic Transmission and Reservoir Potential of Zika, Dengue, and Chikungunya Viruses of Co-located Humans and Long-tailed Macaques in Thailand and Cambodia
Conditions: Dengue Fever; Zika; Vector-Borne Diseases; Chikungunya Intervention: Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 17, 2020 Category: Research Source Type: clinical trials
Impact of Indoor Residual Spraying on Aedes-borne Diseases
Conditions: Aedes-borne Diseases; Dengue; Chikungunya; Zika Intervention: Biological: Targeted Indoor Residual Spraying (TIRS) Sponsors: Emory University; National Institute of Allergy and Infectious Diseases (NIAID) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 13, 2020 Category: Research Source Type: clinical trials
When could human challenge trials be deployed to combat emerging infectious diseases? Lessons from the case of a Zika virus human challenge trial
AbstractHuman challenge trials (HCTs) deliberately infect participants in order to test vaccines and treatments in a controlled setting, rather than enrolling individuals with natural exposure to a disease. HCTs are therefore potentially powerful tools to prepare for future outbreaks of emerging infectious diseases. Yet when an infectious disease is emerging, there is often substantial risk and uncertainty about its complications, and few available interventions, making an HCT ethically complex. In light of the need to consider ethical issues proactively as a part of epidemic preparedness, we use the case of a Zika virus H...
Source: Trials - December 18, 2019 Category: Research Source Type: clinical trials
