TWiV 1063: Childhood paralysis with Kevin Messacar
Kevin Messacar visits the Incubator to discuss his career as a pediatric infectious disease physician, and his work on enteroviruses that are associated with acute flaccid myelitis and other diseases. Host: Vincent Racaniello Guest: Kevin Messacar Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server MicrobeTV store at Cafepress Global Scholar Travel Awards (ASV) Research assistant position in Rosenfeld Lab CBER/FDA (pdf) Emergence of EV-D68 (Microbio Spectr) 2014 outbreak of EV-D68 (J Med Virol) EV-D68 shedding in households (...
Source: This Week in Virology - MP3 Edition - November 19, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 1062: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses coverage with selected vaccines and exemption from school vaccine requirements among children in kindergarten, seasonality of endemic COVID-19, mRNA SARS-CoV-2 vaccination before vs during pregnancy and omicron infection among infants, extracting symptoms from free-text responses using ChatGPT among COVID-19 cases in Hong Kong, SARS-CoV-2 virologic rebound with nirmatrelvir–ritonavir therapy, optimization of antiviral therapy in immunocompromised COVID-19 patients, a study to learn about the study medicines (nirmatrelvir plus ritonavir) in people aged 12 years or older...
Source: This Week in Virology - MP3 Edition - November 18, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 1061: Seasonal COVID and a niche for cervical cancer
TWiV reveals a prediction of the expected endemic seasonality of COVID-19, based on circulation of human coronaviruses, and ecological clearance of vaccine-targeted human papillomaviruses and an increase in circulation of non-targeted virus types. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Kathy Spindler Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server MicrobeTV store at Cafepress Global Scholar Travel Awards (ASV) Research assistant position in Rosenfeld Lab CBER/FDA (pdf) The New City by Dickson Despommi...
Source: This Week in Virology - MP3 Edition - November 12, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 1060: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses CDC expanding testing of international air traveler samples to include flu, RSV, and other respiratory viruses, missed opportunities for preventing congenital syphilis, intrinsic and effective severity of COVID-19 cases infected with the ancestral strain and omicron BA.2 variant in Hong Kong, T-cell immunity against severe acute respiratory syndrome coronavirus 2 measured by an interferon-γ release assay is strongly associated with patient outcomes in vaccinated persons hospitalized with delta or omicron variants, masks during pandemics caused by respiratory pathogens, ...
Source: This Week in Virology - MP3 Edition - November 11, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 1059: Keeping poliovirus out and Ebolavirus in
On this episode of TWiV we discuss unusual properties of monoclonal antibodies: one that that binds the receptor attachment site and blocks infection with all three poliovirus serotypes, and others that inhibit Ebolavirus spread from cell to cell. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Angela Mingarelli Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server MicrobeTV store at Cafepress Global Scholar Travel Awards (ASV) Research assistant position in Rosenfeld Lab CBER/FDA (pdf) Monoclonal antib...
Source: This Week in Virology - MP3 Edition - November 5, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 1058: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses health worker–perceived working conditions and symptoms of poor mental health, Mpox neutralizing antibodies at 6 months from mpox infection or MVA-BN vaccination, newborn and early infant outcomes following maternal COVID-19 vaccination during pregnancy, duration of SARS-CoV-2 culturable virus shedding in children, prescribing outcomes in outpatients treated with nirmatrelvir–ritonavir for COVID-19 in an interdisciplinary community clinic, Nirmatrelvir and molnupiravir and post-COVID-19 condition in older patients, optimal duration of systemic corticosteroids in COVI...
Source: This Week in Virology - MP3 Edition - November 4, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 1057: CMV-based HIV vaccine with Klaus Fr üh
Klaus Früh visits the Incubator to discuss his career and his work on cytomegalovirus-vectored vaccines which are unique in their ability to persistently maintain an immune shield of effector memory T cells, including highly unconventional MHC-II and MHC-E restricted CD8+ T cells. Host: Vincent Racaniello, Rich Condit, and Brianne Barker Guest: Klaus Früh Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server MicrobeTV store at Cafepress Spike shirts at vaccinated.us (promo code Microbetv) Research assistant position in Rosenfeld...
Source: This Week in Virology - MP3 Edition - October 29, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 1056: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses health worker–perceived working conditions and symptoms of poor mental health, Mpox neutralizing antibodies at 6 months from mpox infection or MVA-BN vaccination, newborn and early infant outcomes following maternal COVID-19 vaccination during pregnancy, duration of SARS-CoV-2 culturable virus shedding in children, prescribing outcomes in outpatients treated with nirmatrelvir–ritonavir for COVID-19 in an interdisciplinary community clinic, Nirmatrelvir and molnupiravir and post-COVID-19 condition in older patients, optimal duration of systemic corticosteroids in COVI...
Source: This Week in Virology - MP3 Edition - October 28, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 1055: Vermont viridae
Vincent travels to the University of Vermont to speak with Jason, Emily, Jessica, and Dimitry about their careers and their work on SARS-CoV-2, hantaviruses, poliovirus, influenza virus, and the involvement of viruses in the autoimmune disease multiple sclerosis. Host: Vincent Racaniello Guests: Jason Botten, Emily Bruce, Jessica Crothers, and Dimitry Krementsov Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server MicrobeTV store at Cafepress Spike shirts at vaccinated.us (promo code Microbetv) Research assistant position in Ros...
Source: This Week in Virology - MP3 Edition - October 22, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 1054: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses high Influenza incidence and disease severity among children and adolescents aged (Source: This Week in Virology - MP3 Edition)
Source: This Week in Virology - MP3 Edition - October 21, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 1053: Bird flu in Baltimore
From the Centers for Excellence in Influenza Research and Response meeting in Baltimore, Vincent speaks with Ron Fouchier, Rafael Medina, and Louse Moncla about recent changes in the epidemiology of avian H5N1 influenza virus and the threat to humans and other animals. Host: Vincent Racaniello Guests: Ron Fouchier, Rafael Medina, and Louise Moncla Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server MicrobeTV store at Cafepress Spike shirts at vaccinated.us (promo code Microbetv) Research assistant position in Rosenfeld Lab CBER/...
Source: This Week in Virology - MP3 Edition - October 15, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 1052: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses disease severity of RSV compared with COVID-19 and Influenza among hospitalized adults aged ≥60 years, antiviral efficacy of Molnupiravir versus ritonavir-boosted nirmatrelvir in patients with early symptomatic COVID-19, Nirmatrelvir-Ritonavir and COVID-19 mortality and hospitalization among patients with vulnerability to covid-19 complications, antibiotic use among hospitalized patients with COVID-19 in the United States, one week of oral Camostat vs Placebo in nonhospitalized adults with mild-to-moderate COVID-19, assessment of the available therapeutic approaches fo...
Source: This Week in Virology - MP3 Edition - October 14, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 1051: Like SARS-CoV-2 in the headlights
TWiV reviews the 2023 Nobel Prize in Physiology or Medicine awarded to Katalin Karikó and Drew Weissman for their identification nucleoside base modifications that enabled the development of effective mRNA vaccines against COVID-19, and accelerated mutation of SARS-CoV-2 in white-tailed deer. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Angela Mingarelli Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server MicrobeTV store at Cafepress Spike shirts at vaccinated.us (promo code Microbetv) Research assistant positi...
Source: This Week in Virology - MP3 Edition - October 8, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 1050: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses the effectiveness of maternal mRNA COVID-19 vaccination during pregnancy against COVID-19–associated hospitalizations in infants aged (Source: This Week in Virology - MP3 Edition)
Source: This Week in Virology - MP3 Edition - October 7, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 1049: Long COVID's book of homeostatic cats
TWiV explains how immune profiling was used to identify distinguishing features of Long COVID, and how a co-opted feline endogenous retroviral envelope promotes cell survival by controlling copper transport and homeostasis in cats. Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Brianne Barker Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server MicrobeTV store at Cafepress Spike shirts at vaccinated.us (promo code Microbetv) Research assistant position in Rosenfeld Lab CBER/FDA (pdf) Features of Long COVID (Nature) ERV ...
Source: This Week in Virology - MP3 Edition - October 1, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts