TWiV 950: Prion diseases with Richard Knight
From the European Society for Clinical Virology 2022 Conference in Manchester UK, Vincent speaks with Richard Knight about prion diseases and the outbreak of bovine spongiform encephalitis that led to cases of variant Creutzfeldt-Jakob disease in humans. Host: Vincent Racaniello Guest: Richard Knight Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode National CJD Research and Surveillance Unit Clinical diagnosis of human prion disease (Prog Mol Biol Trans Sci) Variant Creutzfeldt-Jakob disease (Handbook Clin Viral) Creutzfeldt-Jakob disease (Adv Exp Med Bi...
Source: This Week in Virology - MP3 Edition - October 30, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 949: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses progress toward poliomyelitis eradication in Pakistan, polio by the numbers , influenza and COVID-19 vaccination coverage among health care personnel, phase 1/2a safety and immunogenicity of an adenovirus 26 vector RSV vaccine encoding prefusion F in adults 18–50 years and RSV seropositive children 12–24 months, receipt of first and second doses of JYNNEOS vaccine for prevention of Monkeypox, distinguishing SARS-CoV-2 persistence and reinfection, Novavax NVX-COV2373 triggers potent neutralization of Omicron sub-lineages, association between regular physical activity a...
Source: This Week in Virology - MP3 Edition - October 29, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 948: Breathless with David Quammen
David Quammen returns to TWiV to discuss how he wrote his new book ‘Breathless’, a story about the science and the scientists behind the race to understand the pandemic coronavirus SARS-CoV-2. Hosts: Vincent Racaniello, Rich Condit,  Kathy Spindler, and Brianne Barker Guest: David Quammen Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Boston Quammens (TWiV 408) Breathless by David Quammen Spillover by David Quammen Song of the Dodo by David Quammen Timestamps by Jolene. Thanks! Weekly Picks David – Shepherd Brianne – Adventure Aquarium Kathy â€...
Source: This Week in Virology - MP3 Edition - October 23, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 947: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses the prediction of upcoming global infection burden of influenza seasons after relaxation of public health and social measures during the COVID-19 pandemic, severe COVID-19 outcomes after full vaccination of primary schedule and initial boosters, and how successful immunomodulators for treatment of COVID-19 have opened the pathway for comparative trials. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support MicrobeTV with a Spike t-shirt at Vaccinated.US Prediction of upcoming global infection burden...
Source: This Week in Virology - MP3 Edition - October 22, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 946: Poo versus flu
Angela Mingarelli joins TWiV to discuss whether the gut microbiota of bats confers tolerance to influenza virus infection in mice, and primate hemorrhagic fever-causing arteriviruses that can reproduce in human cells and might be capable of infecting humans. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit,  and Brianne Barker Guest: Angela Mingarelli Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Research assistant position at FDA (pdf) Support MicrobeTV with a Spike t-shirt (Vaccinated.us) Bat gut microbiota and flu infection in ...
Source: This Week in Virology - MP3 Edition - October 16, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 945: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses a healthcare-associated infection with Monkeypox virus, air and surface sampling for monkeypox virus in a UK hospital, misrepresentation and nonadherence regarding COVID19 public health measures, tolerability and immunogenicity of an intranasally-administered adenovirus-vectored COVID-19 vaccine, clinical, virologic, and immunologic evaluation of symptomatic rebound following Nirmatrelvir/Ritonavir treatment, early outpatient treatment with Eemdesivir in patients at high risk for severe COVID-19, Molnupiravir plus usual care versus usual care alone as early treatme...
Source: This Week in Virology - MP3 Edition - October 15, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 944: Hacking through Borneo with Kathryn Hanley
Kathryn Hanley joins TWiV to discuss her career and the research in her laboratory on the molecular biology, evolution and ecology of emerging RNA viruses and their insect vectors. Hosts: Vincent Racaniello, Rich Condit,  and Kathy Spindler Guest: Kathryn Hanley Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Research assistant position at FDA (pdf) Support MicrobeTV with a Spike t-shirt (Vaccinated.us) One bite is all it takes (TWiV 587) CREATE-NEO Shifts in Borneo mosquito diversity (Ecosphere) VSV surveillance along Rio Grande (PLoS Path) Virulence a...
Source: This Week in Virology - MP3 Edition - October 9, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 943: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses high points of the multi-national monkeypox outbreaks, monkeypox virus genome mutations, possible occupational infection of healthcare workers with monkeypox virus, rates of monkeypox cases by vaccination status, protection of SARS-CoV-2 infection against reinfection, Paxlovid significantly reduces COVID-19 hospitalizations and deaths, and rebound in COVID19 with and without Paxlovid treatment. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Research assistant position with Amy Rosenfeld (pdf) Support M...
Source: This Week in Virology - MP3 Edition - October 8, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

Public Health with Laurie Garrett: Wastewater Testing
Laurie Garrett discusses the role of wastewater testing in public health and her idea of a device that could be used by anyone to analyze water samples. This podcast is not an episode of TWiV, but I thought it would be of interest to listeners. Laurie Garrett and Vincent Racaniello Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support MicrobeTV with a Spike t-shirt (Vaccinated.us) Coliform testing of water in Florida (YouTube) Declining cost of genome sequencing (Illumina) National wastewater surveillance system (CDC) Advances in detection of viruses in...
Source: This Week in Virology - MP3 Edition - October 4, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 942: Omicron boosters with Paul Offit
Paul Offit returns to TWiV for a discussion of SARS-CoV-2 bivalent boosters containing ancestral and Omicron spike mRNAs, including their composition, why they are being recommended by CDC, and who would benefit the most from them. Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit,  Kathy Spindler, and Brianne Barker Guest: Paul Offit Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Research assistant position at FDA (pdf) Support MicrobeTV with a Spike t-shirt (Vaccinated.us) CDC oversells bivalent booster (Wall St Journal) FDA authorizes biva...
Source: This Week in Virology - MP3 Edition - October 2, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 941: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses increased acute respiratory illnesses among children and adolescents, estimates of monkeypox incubation period, generation time, and reproduction number, rapid increase in suspected SARS-CoV-2 reinfections, interim infection prevention and control recommendations for healthcare personnel during COVID-19, SARS-CoV-2 secondary attack rates in vaccinated and unvaccinated household contacts during replacement of delta with omicron variant, breakthrough infection by SARS-CoV-2 delta and omicron variants elicited immune response comparable to mRNA booster vaccination, inter...
Source: This Week in Virology - MP3 Edition - October 1, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 940: Eddie Holmes in on viral origins
Eddie Holmes joins TWiV to discuss his role in the first release of the SARS-CoV-2 genome sequence, what really happened during the infamous Fauci teleconference, and evidence that the virus came from Nature and not from a lab. Hosts: Vincent Racaniello and Dickson Despommier Guest: Eddie Holmes Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Research assistant position at FDA (pdf) Support MicrobeTV with a Spike t-shirt (Vaccinated.us) Novel 2019 coronavirus genome (Virological) Proximal origins of SARS-CoV-2 (Virological and Nature versions) Original p...
Source: This Week in Virology - MP3 Edition - September 28, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 939: From lizards to Lassa with Tom Monath
Tom Monath joins TWiV to discuss his wide-ranging career that includes medicine, field work and vaccine development while working for the US government, the US military, and multiple biotechnology companies. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Rich Condit Guest: Tom Monath Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Research assistant position at FDA (pdf) Support MicrobeTV with a Spike t-shirt (Vaccinated.us) Fever by John Fuller (Amazon) Crozet BioPharma Timestamps by Jolene. Thanks! Weekly Picks Dickson – Jazz – Small...
Source: This Week in Virology - MP3 Edition - September 25, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 938: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin reviews the public health response to poliovirus in New York, impact of mandatory influenza vaccination, monkeypox in a young infant, health care worker exposure to monkeypox virus, monkeypox testing delays, transmission potential of monkeypox virus, TPOXX trial for monkeypox, detection of SARS-CoV-2 subgenomic mRNA, mucosal IgA against SARS-CoV-2, BNT262b2 against Omicron, awareness and use of SARS-CoV-2 antivirals, comparable outcomes for Bebtelovimab and Nirmatrelvir, and COVID-19 and Alzheimer's disease. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a...
Source: This Week in Virology - MP3 Edition - September 24, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts