SCCMPod-463 CCM: Clazakizumab for COVID-19: Friend or Foe?
Clazakizumab is a monoclonal antibody against human interleukin-6 that may benefit patients hospitalized with severe or critical COVID-19 accompanied by hyperinflammation. Although not yet FDA approved, clinical trials of clazakizumab for treatment of COVID-19 are under way worldwide. Samantha Gambles Farr, MSN, NP-C, CCRN, RNFA, is joined by Bonnie E. Lonze, MD, PhD, to discuss the article, A Randomized Double-Blinded Placebo Controlled Trial of Clazakizumab for the Treatment of COVID-19 Pneumonia With Hyperinflammation, published in the September 2022 issue of Critical Care Medicine. Dr. Lonze is a faculty transplant sur...
Source: SCCM PodCast - iCritical Care - October 6, 2022 Category: Intensive Care Authors: The Society of Critical Care Medicine (SCCM) Tags: Medicine Source Type: podcasts
TWiV 941: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses increased acute respiratory illnesses among children and adolescents, estimates of monkeypox incubation period, generation time, and reproduction number, rapid increase in suspected SARS-CoV-2 reinfections, interim infection prevention and control recommendations for healthcare personnel during COVID-19, SARS-CoV-2 secondary attack rates in vaccinated and unvaccinated household contacts during replacement of delta with omicron variant, breakthrough infection by SARS-CoV-2 delta and omicron variants elicited immune response comparable to mRNA booster vaccination, inter...
Source: This Week in Virology - MP3 Edition - October 1, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
Audio long read: Hybrid brains – the ethics of transplanting human neurons into animals
The development of brain chimaeras – made up of human and animal neurons – is an area of research that has hugely expanded in the past five years. Proponents say that these systems are yielding important insights into health and disease, but others say the chimeras represent an ethical grey zone, because of the potential to blur the line between humans and other animals, or to recapitulate human-like cognition in an animal.This is an audio version of our Feature: Hybrid brains: the ethics of transplanting human neurons into animals Our GDPR privacy policy was updated on August 8, 2022. Visit acast.com/privacy for more ...
Source: Nature Podcast - August 26, 2022 Category: Science Authors: Springer Nature Limited Source Type: podcasts
TWiV 924: TWiV clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses Tecovirimat for treatment of monkeypox, the safety and acceptance of vaccination after multisystem inflammatory syndrome, variants in solid organ transplant recipients, masks for prevention of respiratory virus infections, pre-exposure prophylaxis with Evusheld, the association between Evusheld administration and infection, if repeat administration of casirivimab and imdevimab is well-tolerated, viral and symptom rebound in untreated infection, extended Remdesivir infusion for persistent infection, Baricitinib in patients admitted with infection, and cognitive impa...
Source: This Week in Virology - MP3 Edition - August 6, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
Massive Facebook study reveals a key to social mobility
00:47 The economic benefits of social connectionsBy looking at data gathered from billions of Facebook friendships, researchers have shown that having more connections with people from higher income groups could increase future incomes by 20%. They also show how such connections can be formed, and how schools and other institutions could help to improve peoples’ opportunities in the future.Research Article: Chetty et al.Research Article: Chetty et al.News and Views: The social connections that shape economic prospectsLink to the data11:06 Research HighlightsHow balloons could help measure quakes on Venus, and the parasit...
Source: Nature Podcast - August 3, 2022 Category: Science Authors: Springer Nature Limited Source Type: podcasts
TWiV 906: Long COVID, giant viruses, and smallish pox
TWiV reviews human monkeypox infections, evidence for human Mimivrus infections, and incidence of long COVID in post-vaccine SARS-CoV-2 infections. Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, and Brianne Barker Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Monkeypox update (ProMedMail) Multi-country monkeypox outbreak (WHO) Monkeypox new global threat (Science) Monkeypox outbreak 9 US states (MMWR) Mimivirus in human respiratory samples (Sci Rep) Long COVID after post-vaccination infection (Nat Med) Letters read on TWiV 906 Timestamps b...
Source: This Week in Virology - MP3 Edition - June 5, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 905: COVID-19 clinical update #117 with Dr. Daniel Griffin
In COVID-19 clinical update #117, Dr. Griffin discusses duration of virus shedding, association between pre-exposure to steroids and infection outcome, post-infection subtypes, rehabilitation for post-acute infection, Tixagevimab/Cilgavimab for infection prevention, antibody prophylaxis and vaccination in kidney transplant recipients, remdesivir and bebtelovimab fact sheets for providers, the updated guidelines on treatment with Famotidine, Paxlovid rebound symptom characterizations, antigen test positivity duration, viral dynamics of variants and isolation, association of inflammation in CS fluid, and transmission dynami...
Source: This Week in Virology - MP3 Edition - June 4, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
Robot exercises shoulder cells for better tissue transplants
00:47 The robot shoulder that exercises cellsRecreating the movements that tendon cells experience as they develop in the human body is necessary for growing tissue for transplantation, but this has been difficult to achieve in a laboratory setting. Now, a team has developed a system that uses a robot shoulder to stretch and twist these cells, which they hope could be used to improve the quality of tissue grafts in the future.Research article: Mouthuy et al.Video: A robotic Petri dish: How to grow human cells in a robot shoulder07:56 Research HighlightsA robotic surgeon that works within an MRI chamber, and an ancient huma...
Source: Nature Podcast - June 1, 2022 Category: Science Authors: Springer Nature Limited Source Type: podcasts
X-ray analysis hints at answers to fossil mystery
00:45 The puzzle of PalaeospondylusOver a hundred years ago, archaeologists discovered fossils of the aquatic animal Palaeospondylus. But since then researchers have been unable to place where this animal sits on the tree of life. Now, new analysis of Palaeospondylus’s anatomy might help to solve this mystery.Research article: Hirasawa et al.News and Views: Clues to the identity of the fossil fish Palaeospondylus08:18 Research HighlightsA strong, silk-based version of mother of pearl, and the parrots that use their heads when climbing.Research Highlight: Silk imitates mother of pearl for a tough, eco-friendly materialRes...
Source: Nature Podcast - May 25, 2022 Category: Science Authors: Springer Nature Limited Source Type: podcasts
JAMA Surgery : Proposing a Sex-Adjusted Sodium-Adjusted MELD Score for Liver Transplant Allocation
Interview with Sophoclis P. Alexopoulos, MD, and Julia M. Sealock, BS, authors of Proposing a Sex-Adjusted Sodium-Adjusted MELD Score for Liver Transplant Allocation Hosted by Amalia Cochran, MD. (Source: JAMA Specialty Journals Author Interviews)
Source: JAMA Specialty Journals Author Interviews - May 18, 2022 Category: General Medicine Authors: The JAMA Network Source Type: podcasts
JAMA Dermatology : Nonkeratinocyte Skin Cancer Risk Among Solid Organ Transplant Recipients
Interview with Michael R. Sargen, MD, author of Spectrum of Nonkeratinocyte Skin Cancer Risk Among Solid Organ Transplant Recipients in the US. Hosted by Adewole S. Adamson, MD, MPP. (Source: JAMA Specialty Journals Author Interviews)
Source: JAMA Specialty Journals Author Interviews - March 9, 2022 Category: General Medicine Authors: The JAMA Network Source Type: podcasts
Prevention of Self-harm in Adults With Suicidal Ideation, Symptomatic Omicron and Delta SARS-CoV-2 Infection Following Vaccination, Outcomes of Lung Transplant for COVID-19 ARDS, and more
Editor's Summary by Preeti Malani, MD, Associate Editor of JAMA, the Journal of the American Medical Association, for the February 15, 2022, issue. (Source: JAMA: This Week's Audio Commentary)
Source: JAMA: This Week's Audio Commentary - February 15, 2022 Category: General Medicine Authors: JAMA Network Source Type: podcasts
Fecal transplants in pill form, and gut bacteria that nourish hibernating squirrels
On this week’s show: A pill derived from human feces treats recurrent gut infections, and how a squirrel’s microbiome supplies nitrogen during hibernation
First up this week, Staff Writer Kelly Servick joins host Sarah Crespi to discuss putting the bacterial benefits of human feces in a pill. The hope is to avoid using fecal transplants to treat recurrent gut infections caused by the bacterium Clostridium difficile.
Also this week, Hannah Carey, a professor in the department of comparative biosciences within the school of veterinary medicine at the University of Wisconsin, Madison, talks with Sarah about how ...
Source: Science Magazine Podcast - January 27, 2022 Category: Science Authors: Science Magazine Source Type: podcasts
Fecal transplants in pill form, and gut bacteria that nourish hibernating squirrels
On this week’s show: A pill derived from human feces treats recurrent gut infections, and how a squirrel’s microbiome supplies nitrogen during hibernation
First up this week, Staff Writer Kelly Servick joins host Sarah Crespi to discuss putting the bacterial benefits of human feces in a pill. The hope is to avoid using fecal transplants to treat recurrent gut infections caused by the bacterium Clostridium difficile.
Also this week, Hannah Carey, a professor in the department of comparative biosciences within the school of veterinary medicine at the University of Wisconsin, Madison, talks with Sarah about how ground s...
Source: Science Magazine Podcast - January 27, 2022 Category: Science Authors: Science Magazine Source Type: podcasts
