Debating when death begins, and the fate of abandoned lands
A new approach promises to increase organ transplants but some question whether they should proceed without revisiting the definition of death, and what happens to rural lands when people head to urban centers   First up this week, innovations in organ transplantation lead to ethical debates. Host Sarah Crespi talks with Staff Writer Jennifer Couzin-Frankel and several transplant surgeons and doctors about defining death, technically. Also in this segment: Anji Wall, abdominal transplant surgeon and bioethicist at Baylor University Medical Center Marat Slessarav, consultant intensivist and donation physician at the...
Source: Science Magazine Podcast - May 11, 2023 Category: Science Authors: Science Magazine Source Type: podcasts

Debating when death begins, and the fate of abandoned lands
A new approach promises to increase organ transplants but some question whether they should proceed without revisiting the definition of death, and what happens to rural lands when people head to urban centers   First up this week, innovations in organ transplantation lead to ethical debates. Host Sarah Crespi talks with Staff Writer Jennifer Couzin-Frankel and several transplant surgeons and doctors about defining death, technically. Also in this segment: Anji Wall, abdominal transplant surgeon and bioethicist at Baylor University Medical Center Marat Slessarav, consultant intensivist and donation physician at t...
Source: Science Magazine Podcast - May 11, 2023 Category: Science Authors: Science Magazine Source Type: podcasts

COAPT 5-Year Results'Remarkable,' but Patient Selection Issues Remain
(Source: Medscape Transplantation Podcast)
Source: Medscape Transplantation Podcast - April 7, 2023 Category: Transplant Surgery Authors: Medscape 210869 Source Type: podcasts

The Uncertain Future of the Determination of Brain Death
JAMA Executive Editor Greg Curfman, MD, speaks with Robert D. Truog, MD, MA, director of the Harvard Center for Bioethics, who describes the 2 approaches to the determination of death (cardiovascular death and brain death) and discusses the possibility that the determination of brain death may soon undergo substantial change, with important implications for organ transplantation. Related Content: The Uncertain Future of the Determination of Brain Death (Source: JAMA Author Interviews)
Source: JAMA Author Interviews - March 29, 2023 Category: General Medicine Authors: JAMA Network Source Type: podcasts

Somatic Reprogramming May Create Biological Pacemakers
(Source: Medscape Transplantation Podcast)
Source: Medscape Transplantation Podcast - March 23, 2023 Category: Transplant Surgery Authors: Medscape 210869 Source Type: podcasts

Can Particles in Dairy and Beef Cause Cancer and MS?
(Source: Medscape Transplantation Podcast)
Source: Medscape Transplantation Podcast - March 13, 2023 Category: Transplant Surgery Authors: Medscape 210869 Source Type: podcasts

TWiV 990: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses confronting the evolution and expansion of anti-vaccine activism in the USA in the COVID-19 era, the effectiveness of maternal Influenza vaccination in Peru, characteristics and predictors of persistent symptoms post-COVID-19 in children and young people, parental nonadherence to health policy recommendations for prevention of COVID-19 transmission among children, community-onset bacterial coinfection in children critically ill with SARS-CoV-2 infection, bivalent booster effectiveness against severe COVID-19 outcomes in Finland, viral kinetics of sequential SARS-CoV-2 inf...
Source: This Week in Virology - MP3 Edition - March 11, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 982: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses the consistency of COVID-19 trial preprints with published reports and impact for decision making, the negative effect of preexisting immunity on Influenza vaccine responses transcends the impact of vaccine formulation type and vaccination history, highly pathogenic avian influenza A(H5N1) virus infection in farmed minks in Spain, Peru confirms H5N1 avian flu in marine mammals, prior vaccination enhances immune responses during SARS-CoV-2 breakthrough infection with early activation of memory T cells followed by production of potent neutralizing antibodies, bacillu...
Source: This Week in Virology - MP3 Edition - February 11, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

A controversial dam in the Amazon unites Indigenous people and scientists, and transplanting mitochondria to treat rare diseases
Keeping an eye on the largest hydroelectric project in the Amazon basin, and helping patients with deletions in their mitochondrial DNA We are starting off the new year with producer Kevin McLean and freelance science journalist Sofia Moutinho. They discuss a controversial dam in the Brazilian Amazon and how Indigenous peoples and researchers are trying to monitor its impact. Then, host Sarah Crespi speaks with Elad Jacoby, an expert in pediatric hematology and oncology at the Sheba Medical Center and Tel Aviv University, about the many wonders of mitochondria. In a recent Science Translational Medicine paper, his team t...
Source: Science Magazine Podcast - January 5, 2023 Category: Science Authors: Science Magazine Source Type: podcasts

A controversial dam in the Amazon unites Indigenous people and scientists, and transplanting mitochondria to treat rare diseases
Keeping an eye on the largest hydroelectric project in the Amazon basin, and helping patients with deletions in their mitochondrial DNA We are starting off the new year with producer Kevin McLean and freelance science journalist Sofia Moutinho. They discuss a controversial dam in the Brazilian Amazon and how Indigenous peoples and researchers are trying to monitor its impact. Then, host Sarah Crespi speaks with Elad Jacoby, an expert in pediatric hematology and oncology at the Sheba Medical Center and Tel Aviv University, about the many wonders of mitochondria. In a recent Science Translational Medicine paper, his team t...
Source: Science Magazine Podcast - January 5, 2023 Category: Science Authors: Science Magazine Source Type: podcasts

JAMA Internal Medicine : Association of Pretransplant Coronary Heart Disease Testing With Early Kidney Transplant Outcomes
Interview with Xingxing S. Cheng, MD, MS, author of Association of Pretransplant Coronary Heart Disease Testing With Early Kidney Transplant Outcomes. Hosted by Rita Redberg, MD. Related Content: Association of Pretransplant Coronary Heart Disease Testing With Early Kidney Transplant Outcomes (Source: JAMA Specialty Journals Author Interviews)
Source: JAMA Specialty Journals Author Interviews - January 3, 2023 Category: General Medicine Authors: The JAMA Network Source Type: podcasts

SCCM Pod-463 CCM: Clazakizumab for COVID-19: Friend or Foe?
Clazakizumab is a monoclonal antibody against human interleukin-6 that may benefit patients hospitalized with severe or critical COVID-19 accompanied by hyperinflammation. Although not yet FDA approved, clinical trials of clazakizumab for treatment of COVID-19 are under way worldwide. Samantha Gambles Farr, MSN, NP-C, CCRN, RNFA, is joined by Bonnie E. Lonze, MD, PhD, to discuss the article, A Randomized Double-Blinded Placebo Controlled Trial of Clazakizumab for the Treatment of COVID-19 Pneumonia With Hyperinflammation, published in the September 2022 issue of Critical Care Medicine. Dr. Lonze is a faculty transplant sur...
Source: SCCM PodCast - iCritical Care - December 21, 2022 Category: Intensive Care Authors: The Society of Critical Care Medicine (SCCM) Tags: Medicine Source Type: podcasts

TWiV 955: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses the four things to know about RSV, the burden of respiratory syncytial virus in healthy term-born infants in Europe, the diagnostic accuracy of rapid diagnostic tests for Ebola virus disease, evaluating the accuracy of self-collected swabs for the diagnosis of monkeypox, tecovirimat is effective against human monkeypox virus in vitro at nanomolar concentrations, acute and postacute sequelae associated with SARS-CoV-2 reinfection, clinical course of SARS-CoV-2 infection and recovery in lung transplant recipients, effectiveness of a third BNT162b2 mRNA COVID-19 vaccina...
Source: This Week in Virology - MP3 Edition - November 19, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 949: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses progress toward poliomyelitis eradication in Pakistan, polio by the numbers , influenza and COVID-19 vaccination coverage among health care personnel, phase 1/2a safety and immunogenicity of an adenovirus 26 vector RSV vaccine encoding prefusion F in adults 18–50 years and RSV seropositive children 12–24 months, receipt of first and second doses of JYNNEOS vaccine for prevention of Monkeypox, distinguishing SARS-CoV-2 persistence and reinfection, Novavax NVX-COV2373 triggers potent neutralization of Omicron sub-lineages, association between regular physical activity a...
Source: This Week in Virology - MP3 Edition - October 29, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

Human brain organoids implanted into rats could offer new way to model disease
In this episode:00:45 Implanted brain organoids could offer new insights into diseaseBrain organoids — lab-grown, self-organizing structures made of stem cells — are used in research to better understand brain development and disease progression. However, these structures lack connections seen in real brains, limiting their usefulness. To overcome this, a team has now transplanted human organoids into the brains of newborn rats, showing that these implanted organoids respond to stimuli and could influence the animals’ behaviour.Research article: Revah et al.News and Views: Human brain organoids influence rat behaviou...
Source: Nature Podcast - October 12, 2022 Category: Science Authors: Springer Nature Limited Source Type: podcasts