Mutant cells in the esophagus, and protecting farmers from dangerous pesticide exposure
As you age, your cells divide over and over again, leading to minute changes in their genomes. New research reveals that in the lining of the esophagus, mutant cells run rampant, fighting for dominance over normal cells. But they do this without causing any detectable damage or cancer. Host Sarah Crespi talks to Phil Jones, a professor of cancer development at the University of Cambridge in the United Kingdom, about what these genome changes can tell us about aging and cancer, and how some of the mutations might be good for you. Most Western farmers apply their pesticides using drones and machinery, but in less developed...
Source: Science Magazine Podcast - October 18, 2018 Category: Science Authors: Science Tags: Scientific Community Source Type: podcasts

Precision medicine in lymphoma
Precision medicine is improving outcomes, toxicity and disease management in trials and routine clinical practice. Anas Younes, MD, from the Memorial Sloan Kettering Cancer Center, New York City, NY, ... Author: VJHemOnc Added: 09/28/2018 (Source: Oncology Tube)
Source: Oncology Tube - September 28, 2018 Category: Cancer & Oncology Source Type: podcasts

The future of PCB-laden orca whales, and doing genomics work with Indigenous people
Science has often treated Indigenous people as resources for research —especially when it comes to genomics. Now, Indigenous people are exploring how this type of study can be conducted in a way that respects their people and traditions. Meagan Cantwell talks with contributing correspondent Lizzie Wade about a summer workshop for Indigenous scientists that aims to s tart a new chapter in genomics. We’ve known for decades that PCBs—polychlorinated biphenyls—are toxic and carcinogenic. In the 1970s and 1980s, these compounds were phased out of use in industrial and electronic applications, worldwide. But they are st...
Source: Science Magazine Podcast - September 27, 2018 Category: Science Authors: Science Tags: Scientific Community Source Type: podcasts

The future of PCB-laden orca whales, and doing genomics work with Indigenous people
Science has often treated Indigenous people as resources for research —especially when it comes to genomics. Now, Indigenous people are exploring how this type of study can be conducted in a way that respects their people and traditions. Meagan Cantwell talks with contributing correspondent Lizzie Wade about a summer workshop for Indigenous scientists that aims to s tart a new chapter in genomics. We’ve known for decades that PCBs—polychlorinated biphenyls—are toxic and carcinogenic. In the 1970s and 1980s, these compounds were phased out of use in industrial and electronic applications, worldwide. But they are sti...
Source: Science Magazine Podcast - September 27, 2018 Category: Science Authors: Science Tags: Scientific Community Source Type: podcasts

The future of PCB-laden orca whales, and doing genomics work with Indigenous people
Science has often treated Indigenous people as resources for research—especially when it comes to genomics. Now, Indigenous people are exploring how this type of study can be conducted in a way that respects their people and traditions. Meagan Cantwell talks with contributing correspondent Lizzie Wade about a summer workshop for Indigenous scientists that aims to start a new chapter in genomics. We’ve known for decades that PCBs—polychlorinated biphenyls—are toxic and carcinogenic. In the 1970s and 1980s, these compounds were phased out of use in industrial and electronic applications, worldwide. But they are st...
Source: Science Magazine Podcast - September 27, 2018 Category: Science Authors: Science Magazine Source Type: podcasts

The future of PCB-laden orca whales, and doing genomics work with Indigenous people
Science has often treated Indigenous people as resources for research —especially when it comes to genomics. Now, Indigenous people are exploring how this type of study can be conducted in a way that respects their people and traditions. Meagan Cantwell talks with contributing correspondent Lizzie Wade about a summer workshop for Indigenous scientists that aims to s tart a new chapter in genomics. We’ve known for decades that PCBs—polychlorinated biphenyls—are toxic and carcinogenic. In the 1970s and 1980s, these compounds were phased out of use in industrial and electronic applications, worldwide. But they are st...
Source: Science Magazine Podcast - September 27, 2018 Category: Science Authors: Science Tags: Scientific Community Source Type: podcasts

The future of PCB-laden orca whales, and doing genomics work with Indigenous people
Science has often treated Indigenous people as resources for research —especially when it comes to genomics. Now, Indigenous people are exploring how this type of study can be conducted in a way that respects their people and traditions. Meagan Cantwell talks with contributing correspondent Lizzie Wade about a summer workshop for Indigenous scientists that aims to s tart a new chapter in genomics. We’ve known for decades that PCBs—polychlorinated biphenyls—are toxic and carcinogenic. In the 1970s and 1980s, these compounds were phased out of use in industrial and electronic applications, worldwide. But they are sti...
Source: Science Magazine Podcast - September 27, 2018 Category: Science Authors: Science Tags: Scientific Community Source Type: podcasts

Identifying patient subgroups to improve outcome, resistance and toxicity in CAR T
CAR T-cells have the potential to revolutionize the field of hematological oncology, however despite impressive efficacy data from CAR T products, some patients develop resistance, have poor outcomes,... Author: VJHemOnc Added: 09/19/2018 (Source: Oncology Tube)
Source: Oncology Tube - September 19, 2018 Category: Cancer & Oncology Source Type: podcasts

The importance of precision immunotherapy: cost, benefit & amp; toxicity
In recent years, there has been a massive increase in the number of different immunotherapeutic agents that can be used in the treatment of cancer. In this interview, Giorgio Scagliotti, MD, PhD, from... Author: VJOncology Added: 08/29/2018 (Source: Oncology Tube)
Source: Oncology Tube - August 29, 2018 Category: Cancer & Oncology Source Type: podcasts

ASCO 2018 Head and Neck Roundtable - Attempts to Decrease Toxicity of Chemoradiotherapy
Drs Jared Weiss and Joshua Bauml discuss advances in treatment for head and neck cancer from ASCO 2018. Author: cancergrace Added: 08/21/2018 (Source: Oncology Tube)
Source: Oncology Tube - August 21, 2018 Category: Cancer & Oncology Source Type: podcasts

ADD-Can Kyprolis (carfilzomib) be administered once a week, rather than twice a week?
In this weeks video, Dr. Brian G.M. Durie explains how the ARROW study demonstrated efficacy and low toxicity for weekly dosing of carfilzomib. <br /><br />BOTTOM LINE: Ensure your doctor is aware of the ARR... Author: InternationalMyelomaFoundation Added: 08/06/2018 (Source: Oncology Tube)
Source: Oncology Tube - August 6, 2018 Category: Cancer & Oncology Source Type: podcasts

A breakthrough for oral mucositis management with avisopasem manganese
Locally advanced head and neck cancer is treated with chemotherapy and radiation as standard, with an aim to cure the disease. Unfortunately, this therapy is associated with severe toxicity, primarily... Author: VJOncology Added: 08/06/2018 (Source: Oncology Tube)
Source: Oncology Tube - August 6, 2018 Category: Cancer & Oncology Source Type: podcasts

A breakthrough for oral mucositis management with avisopasem manganese
Locally advanced head and neck cancer is treated with chemotherapy and radiation as standard, with an aim to cure the disease. Unfortunately, this therapy is associated with severe toxicity, primarily... Author: VJHemOnc Added: 08/06/2018 (Source: Oncology Tube)
Source: Oncology Tube - August 6, 2018 Category: Cancer & Oncology Source Type: podcasts

Comparing CAR T-cell toxicity in ALL and lymphoma
While CAR T-cells are a potentially revolutionary therapy option across a variety of cancer types, their associated side effects include cytokine release syndrome (CRS) and neurotoxicity. Here, Stepha... Author: VJHemOnc Added: 07/30/2018 (Source: Oncology Tube)
Source: Oncology Tube - July 30, 2018 Category: Cancer & Oncology Source Type: podcasts

Improved survival, toxicity & amp; QoL with pembrolizumab in head and neck cancer
Prognoses for patients with relapsed metastatic head and neck cancer that has progressed on prior platinum therapy are poor. Here, Kevin Harrington, PhD, MBBS, of the Institute of Cancer Research and ... Author: VJOncology Added: 07/27/2018 (Source: Oncology Tube)
Source: Oncology Tube - July 27, 2018 Category: Cancer & Oncology Source Type: podcasts