TWiV 1031: Death on the West Nile
TWiV notes the passing of virologist Michael BA Oldstone, a study to assess the performance of rapid antigen tests to detect symptomatic and asymptomatic SARS-CoV-2 infection, and the presence of antibodies to type I interferons in ~40% of patients with West Nile virus encephalitis. Hosts: Vincent Racaniello, Rich Condit, and Alan Dove Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server MicrobeTV store at Cafepress Position in Rosenfeld Laboratory (pdf) XKCD on antivaxxers RFK Jr. CDC or FDA head? (Politico) Performance of rapid...
Source: This Week in Virology - MP3 Edition - July 30, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

Facebook ‘echo chamber’ has little impact on polarized views, according to study
In this episode:How tweaking social media algorithms affects polarizationSocieties are becoming increasingly polarized, with people reportedly shunning those with differing political views. Social media is often thought to be exacerbating these divides, by creating echo chambers and filtering out dissimilar views. Many hoped that tweaking the algorithms that drive these platforms could reduce polarization. But, a group of studies show that such changes have little to no affect on polarization, implying that solutions to this issue are trickier than previously thought.Research Article: Nyhan et al.News and Views: Influence ...
Source: Nature Podcast - July 27, 2023 Category: Science Authors: Springer Nature Limited Source Type: podcasts

TWiV 1026: Debunking RFK Jr. ’s vaccine funk with Dan Wilson
Dan Wilson returns to TWiV to debunk vaccine misinformation by RFK Jr. during his recent appearance on the Joe Rogan Experience. Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, Kathy Spindler, and Brianne Barker Guest: Dan Wilson Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server Joe Rogan’s worst misinformation yet, with RFK Jr. (YouTube) Every first vaccine has been tested in placebo-controlled trials before going to market. Polio Measles HPV COVID-19 HepB Haemophilus influenzae B Pertussis Diphtheria Tetanu...
Source: This Week in Virology - MP3 Edition - July 16, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 1025: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses the new risk assessment for the H5N1 avian flu viruses, the development of monoclonal antibody-based blocking ELISA for detecting SARS-CoV-2 exposure in animals, repeated antibiotic exposure and risk of hospitalization and death following COVID-19 infection, COVID-19 rebound study: a prospective cohort study to evaluate viral and symptom rebound differences in participants treated with Nirmatrelvir plus Ritonavir versus untreated controls, exaggerated blood pressure elevation in response to orthostatic challenge a post-acute sequelae of SARS-CoV-2 infection (PASC) after ...
Source: This Week in Virology - MP3 Edition - July 15, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

The AI special issue, adding empathy to robots, and scientists leaving Arecibo
Science’s NextGen voices share their thoughts on artificial intelligence, how to avoid creating sociopathic robots, and a visit to a historic observatory as researchers pack their bags   As part of a Science special issue on finding a place for artificial intelligence (AI) in science and society, Producer Kevin McLean shares voices from the next generation of researchers. We hear from students about how they think human scientists will still need to work alongside AI in the future.   Continuing the AI theme, we learn about instilling empathy to get better decisions from AI. Researcher Leonardo Christov-Moore, a neu...
Source: Science Magazine Podcast - July 13, 2023 Category: Science Authors: Science Magazine Source Type: podcasts

The AI special issue, adding empathy to robots, and scientists leaving Arecibo
Science’s NextGen voices share their thoughts on artificial intelligence, how to avoid creating sociopathic robots, and a visit to a historic observatory as researchers pack their bags   As part of a Science special issue on finding a place for artificial intelligence (AI) in science and society, Producer Kevin McLean shares voices from the next generation of researchers. We hear from students about how they think human scientists will still need to work alongside AI in the future.   Continuing the AI theme, we learn about instilling empathy to get better decisions from AI. Researcher Leonardo Christov-Moore, a neu...
Source: Science Magazine Podcast - July 13, 2023 Category: Science Authors: Science Magazine Source Type: podcasts

Genomic Sequencing for Ill Newborns
The performance of whole-genome sequencing in comparison with targeted genomic testing methods is not well understood. In this podcast, JAMA Associate Editor W. Gregory Feero, MD, PHD, interviews author Jill L. Maron, MD, MPH, of the Women and Infants Hospital of Rhode Island about a study of whole-genome sequencing vs a commercially available targeted genetic testing platform for diagnosing ill neonates with suspected genetic conditions. Related Content: Rapid Whole-Genomic Sequencing and a Targeted Neonatal Gene Panel in Infants With a Suspected Genetic Disorder (Source: JAMA Author Interviews)
Source: JAMA Author Interviews - July 11, 2023 Category: General Medicine Authors: JAMA Network Source Type: podcasts

TWiV 1022: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses autochthonous leprosy in the United States, a systematic review to identify novel clinical characteristics of Mpox virus infection and therapeutic and preventive strategies to combat the virus, two-year duration of immunity of inactivated poliovirus vaccine, evaluation of novel oral polio vaccine type 2 SIA impact in a large outbreak of circulating vaccine-derived poliovirus in Nigeria, performance of rapid antigen tests to detect symptomatic and asymptomatic SARS-CoV-2 Infection, effectiveness of the COVID-19 bivalent vaccine, oral Nirmatrelvir and Ritonavir for COVID-1...
Source: This Week in Virology - MP3 Edition - July 8, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

Diabetes Core Update – July 2023
Diabetes Core Update is a monthly podcast that presents and discusses the latest clinically relevant articles from the American Diabetes Association’s four science and medical journals – Diabetes, Diabetes Care, Clinical Diabetes, and Diabetes Spectrum. Each episode is approximately 25 minutes long and presents 5-6 recently published articles from ADA journals. Intended for practicing physicians and health care professionals, Diabetes Core Update discusses how the latest research and information published in journals of the American Diabetes Association are relevant to clinical practice and can be applied in a treatmen...
Source: Diabetes Core Update - June 30, 2023 Category: Endocrinology Authors: American Diabetes Association Source Type: podcasts

Talk Evidence - post pandemic pruning, breast cancer screening, and orphan drugs
In this episode of Talk Evidence,  Helen Macdonald, Joe Ross, and Juan Franco are back to update us on what's happening in the world of medical evidence. Firstly, the news about the end of the covid-19 pandemic was trumpeted, but the changes to research funding have been more quite - and the team discuss what this means for ongoing work to understand the effects of covid, but also in terms of preparedness for the next pandemic. Next, breast cancer screening recommendations, in the USA, have been reduced from women over the age of 50, to those over the age of 40. We discuss the modelling study which lead to that recommenda...
Source: The BMJ Podcast - June 30, 2023 Category: General Medicine Authors: BMJ Group Source Type: podcasts

The Costs of Quality Reporting
US hospitals report data on numerous quality metrics to government and independent rating organizations, but the cost of doing so is not well known. JAMA Associate Editor Karen E. Joynt Maddox, MD, discusses a new study that examines just how many quality metrics hospitals have to report, and attempts to quantify how much data collection and reporting costs in hours and dollars, with corresponding author Stephen A. Berry MD, PhD, Johns Hopkins University, Baltimore, Maryland. Related Content: The Volume and Cost of Quality Metric Reporting (Source: JAMA Author Interviews)
Source: JAMA Author Interviews - June 27, 2023 Category: General Medicine Authors: JAMA Network Source Type: podcasts

What IBM's result means for quantum computing
In this episode:00:47 How to make quantum computers ready for real world applicationsQuantum computers have long held the promise of being able to perform tasks that classical computers can’t. However, despite this promise, there have been few applications that can only be accomplished by a quantum computer. Now though, researchers show that a quantum computer can resolve a physics problem concerning the orientation of quantum particles in a 2D material, which is difficult to accomplish with a ‘regular’ machine. They hope that this shows how quantum computers could be applied in real world research applications in th...
Source: Nature Podcast - June 14, 2023 Category: Science Authors: Springer Nature Limited Source Type: podcasts

Diabetes Core Update – June 2023
Diabetes Core Update is a monthly podcast that presents and discusses the latest clinically relevant articles from the American Diabetes Association’s four science and medical journals – Diabetes, Diabetes Care, Clinical Diabetes, and Diabetes Spectrum. Each episode is approximately 25 minutes long and presents 5-6 recently published articles from ADA journals. Intended for practicing physicians and health care professionals, Diabetes Core Update d     iscusses how the latest research and information published in journals of the American Diabetes Association are relevant to clinical practice and can be applied in a...
Source: Diabetes Core Update - June 8, 2023 Category: Endocrinology Authors: American Diabetes Association Source Type: podcasts

A brain circuit for infanticide, in mice
In this episode:00:46 The mouse brain circuit controlling infanticidal behaviourIn mammals, infanticide is a relatively common behaviour, but not a default one. For example, virgin female mice will often kill young produced by other females, but this behaviour disappears when they become mothers themselves. To understand this switch, researchers have identified a brain circuit associated with infanticidal behaviour that gets switched off after mice give birth. They hope that by better understanding this circuit it could inform why animals engage in such behaviours.Research article: Mei et al.Research Briefing: A battle bet...
Source: Nature Podcast - June 7, 2023 Category: Science Authors: Springer Nature Limited Source Type: podcasts

TWiV 1012: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses the potential for recurrent Mpox outbreaks among gay, bisexual, and other men who have sex with men, association between SARS-CoV-2 variants and frequency of acute symptoms, prospective study of key correlates for household transmission of SARS-CoV-2, Pfizer’s PAXLOVID™ receiving FDA approval for adult patients at high risk of progression to severe COVID-19, efficacy and safety of antimicrobial stewardship prospective audit and feedback in patients hospitalized with COVID-19, development of a definition of postacute sequelae of SARS-CoV-2 infection, COVID-19 and risk...
Source: This Week in Virology - MP3 Edition - June 3, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts