The Effect of Continuous Positive Airway Pressure (CPAP) Therapy on Serum Caspase-3 Level in Patients with Obstructive Sleep Apnea (OSA)
CONCLUSION: The results of this study did not reveal a relationship between the severity of OSA and caspase-3 levels. However, blood caspase-3 levels decreased as treatment compliance increased, suggesting that CPAP treatment may correct increased apoptosis in OSA. There is a need for more comprehensive studies on this issue.PMID:38683249 | DOI:10.1007/s11325-024-03039-8 (Source: Sleep and Breathing)
Source: Sleep and Breathing - April 29, 2024 Category: Sleep Medicine Authors: Mustafa Kemal Kaypak Ali Nihat Annakkaya Fatih Davran P ınar Yıldız Gülhan U ğur Yüregir Source Type: research

Severity of sleep apnea as a prognostic factor for mortality in patients with multiple system atrophy
We determined whether the severity of sleep apnea increases the risk of mortality in patients with multiple system atrophy (MSA) with and without stridor.MethodsThis retrospective study included patients who underwent polysomnography within one year after diagnosis of probable MSA. Stridor, sleep apnea, and arousal from sleep were determined using full-night polysomnography. Disease severity was measured using the Unified MSA Rating Scale (UMSARS). Survival data were collected and analyzed using Cox regression analysis. (Source: Parkinsonism and Related Disorders)
Source: Parkinsonism and Related Disorders - April 29, 2024 Category: Neurology Authors: Sungyang Jo, Tae-Young Kim, Yong Seok Lee, Eun-Jae Lee, Sangjin Lee, Jihyun Lee, Sun Ju Chung, Sang-Ahm Lee Source Type: research

The Effect of Continuous Positive Airway Pressure (CPAP) Therapy on Serum Caspase-3 Level in Patients with Obstructive Sleep Apnea (OSA)
ConclusionThe results of this study did not reveal a relationship between the severity of OSA and caspase-3 levels. However, blood caspase-3 levels decreased as treatment compliance increased, suggesting that CPAP treatment may correct increased apoptosis in OSA. There is a need for more comprehensive studies on this issue. (Source: Sleep and Breathing)
Source: Sleep and Breathing - April 29, 2024 Category: Respiratory Medicine Source Type: research

A gated recurrent unit model based on ultrasound images of dynamic tongue movement for determining the severity of obstructive sleep apnea
This study endeavors to bridge this gap by capturing US images of DTM dynamics during wakefulness, encompassing transitions from normal breathing (NB) to the performance of the Müller maneuver (MM) in a cohort of 53 patients. Leveraging the modified optical flow method (MOFM), the trajectories of patients' DTM were tracked, facililtating the extraction of 27 parameters vital for model training. These parameters encompassed nine-point lateral movement, nine-point axial movement, and nine-point total displacement of the tongue, resulting in a dataset of 186,030 samples. The gated recurrent unit (GRU) method, renowned for it...
Source: Ultrasonics - April 28, 2024 Category: Physics Authors: Cyrel Ontimare Manlises Jeng-Wen Chen Chih-Chung Huang Source Type: research

A gated recurrent unit model based on ultrasound images of dynamic tongue movement for determining the severity of obstructive sleep apnea
This study endeavors to bridge this gap by capturing US images of DTM dynamics during wakefulness, encompassing transitions from normal breathing (NB) to the performance of the Müller maneuver (MM) in a cohort of 53 patients. Leveraging the modified optical flow method (MOFM), the trajectories of patients' DTM were tracked, facililtating the extraction of 27 parameters vital for model training. These parameters encompassed nine-point lateral movement, nine-point axial movement, and nine-point total displacement of the tongue, resulting in a dataset of 186,030 samples. The gated recurrent unit (GRU) method, renowned for it...
Source: Ultrasonics - April 28, 2024 Category: Physics Authors: Cyrel Ontimare Manlises Jeng-Wen Chen Chih-Chung Huang Source Type: research

Sleep Apnea in Children and Adults
OTOLARYNGOLOGIC CLINICS OF NORTH AMERICA (Source: Otolaryngologic clinics of North America)
Source: Otolaryngologic clinics of North America - April 27, 2024 Category: ENT & OMF Authors: Stacey L. Ishman, Carol Li, Reena Dhanda Patil Source Type: research

Altered functional connectivity of cerebellar subregions in male patients with obstructive sleep apnea: A resting-state fMRI study
ConclusionThe cerebellum is functionally lateralized and closely linked to the posterior default mode network. Higher FC is related to cognition, emotion, language, and sleep in OSA. Abnormal FC may offer new neuroimaging evidence and insights for a deeper comprehension of OSA-related alterations.Graphical AbstractThis study reveals altered resting-state functional connectivity in the cerebellum (8 cerebellar subregions) of obstructive sleep apnea (OSA) patients. These changes correlate with cognitive, emotional, linguistic, and sleep deficits, suggesting functional impairments and compensation in the cerebellum of OSA pat...
Source: Neuroradiology - April 27, 2024 Category: Radiology Source Type: research

Sensors, Vol. 24, Pages 2803: In-Laboratory Polysomnography Worsens Obstructive Sleep Apnea by Changing Body Position Compared to Home Testing
Conclusions: In-lab polysomnography may artificially increase OSA severity in a subset of patients by inducing marked changes in body position compared to home tests. The location of the sleep test seems to interfere with the evaluation of patients with more severe OSA. (Source: Sensors)
Source: Sensors - April 27, 2024 Category: Biotechnology Authors: Raquel Chartuni Pereira Teixeira Michel Burihan Cahali Tags: Article Source Type: research

Assessment of Sleep Disorders in Patients with CVID
AbstractInborn errors of immunity have been associated with reduced health-related quality of life and increased fatigue. Sleep disorders, which have been shown to contribute to fatigue and other health concerns, are prevalent in the general population, but there are limited studies evaluating these conditions in patients with common variable immunodeficiency (CVID). Our aim was to evaluate the prevalence of fatigue, sleep disturbances, and sleep-disordered breathing in adults with CVID. Patients completed 4 validated, self-administered questionnaires and a 1-night disposable home sleep apnea test. Our results demonstrated...
Source: Journal of Clinical Immunology - April 27, 2024 Category: Allergy & Immunology Source Type: research

Wireless breathable face mask sensor for spatiotemporal 2D respiration profiling and respiratory diagnosis
In this study, we introduced an air-permeable, stretchable, and a pixelated pressure sensor that can be integrated into a commercial face mask. The mask sensor showed a strain-independent pressure-sensing performance, providing 2D pressure profiles for exhalation and inhalation. Real-time 2D respiration profiles could monitor various respiratory behaviors, such as oral/nasal breathing, clogged nose, out-of-breath, and coughing. Furthermore, they could detect respiratory diseases, such as rhinitis, sleep apnea, and pneumonia. The 2D respiratory profiling mask sensor is expected to be employed for remote respiration monitori...
Source: Biomaterials - April 26, 2024 Category: Materials Science Authors: Jaehyun Kim Heesung Roh Sungmin Moon Cheonhoo Jeon Seunggoo Baek Woosung Cho Jae-Yoon Sim Unyong Jeong Source Type: research

Wireless breathable face mask sensor for spatiotemporal 2D respiration profiling and respiratory diagnosis
In this study, we introduced an air-permeable, stretchable, and a pixelated pressure sensor that can be integrated into a commercial face mask. The mask sensor showed a strain-independent pressure-sensing performance, providing 2D pressure profiles for exhalation and inhalation. Real-time 2D respiration profiles could monitor various respiratory behaviors, such as oral/nasal breathing, clogged nose, out-of-breath, and coughing. Furthermore, they could detect respiratory diseases, such as rhinitis, sleep apnea, and pneumonia. The 2D respiratory profiling mask sensor is expected to be employed for remote respiration monitori...
Source: Biomaterials - April 26, 2024 Category: Materials Science Authors: Jaehyun Kim Heesung Roh Sungmin Moon Cheonhoo Jeon Seunggoo Baek Woosung Cho Jae-Yoon Sim Unyong Jeong Source Type: research

Prevalence of obstructive sleep apnea in patients with chronic obstructive pulmonary disease in Vietnam
CONCLUSIONS: The prevalence of obstructive sleep apnea in patients with chronic obstructive pulmonary disease in Vietnam was 42.1% for an AHI of ≥ 15 events/h.PMID:38662313 | DOI:10.1007/s11325-024-03035-y (Source: Sleep and Breathing)
Source: Sleep and Breathing - April 25, 2024 Category: Sleep Medicine Authors: Bao Khac Le Minh Hoang Source Type: research

Prevalence of obstructive sleep apnea in patients with chronic obstructive pulmonary disease in Vietnam
CONCLUSIONS: The prevalence of obstructive sleep apnea in patients with chronic obstructive pulmonary disease in Vietnam was 42.1% for an AHI of ≥ 15 events/h.PMID:38662313 | DOI:10.1007/s11325-024-03035-y (Source: Sleep and Breathing)
Source: Sleep and Breathing - April 25, 2024 Category: Sleep Medicine Authors: Bao Khac Le Minh Hoang Source Type: research

Prevalence of obstructive sleep apnea in patients with chronic obstructive pulmonary disease in Vietnam
CONCLUSIONS: The prevalence of obstructive sleep apnea in patients with chronic obstructive pulmonary disease in Vietnam was 42.1% for an AHI of ≥ 15 events/h.PMID:38662313 | DOI:10.1007/s11325-024-03035-y (Source: Sleep and Breathing)
Source: Sleep and Breathing - April 25, 2024 Category: Sleep Medicine Authors: Bao Khac Le Minh Hoang Source Type: research