Sertraline, brand named Zoloft, improves functioning in young children with fragile X
Treatment with sertraline may provide nominal but important improvements in cognition and social participation in very young children with fragile X syndrome, the most common genetic cause of intellectual disability and the leading single-gene cause of autism, a study has found. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - August 26, 2016 Category: Science Source Type: news

Case series: 8 patients exposed to phony alprazolam (Xanax) containing fentanyl and/or etizolam
3 out of 5 stars Adverse Effects From Counterfeit Alprazolam Tablets. Arens AM et al. Ann Emerg Med 2016 Aug 8 [Epub ahead of print] Reference In March of this year,there were 9 deaths reported in Pinellas County, Florida (the Tampa/St. Petersburg area) associated with fake alprazolam (Xanax) tablets containing fentanyl. Earlier, similar counterfeit pills had been seen around San Francisco and in Monroe County Southern Illinois. This letter, from the University of California-San Francisco and the California Poison Control System describes 8 cases — including 1 cardiac arrest — from that region. An additional victim ...
Source: The Poison Review - August 25, 2016 Category: Toxicology Authors: Leon Gussow Tags: Medical alprazolam counterfeit etizolam fake phony xanax Source Type: news

Asynchronicity of organic and psychiatric symptoms in a case of sertraline intoxication - Pitzianti M, Marciano S, Minnei M, Baratta A, Pasini A.
Sertraline is a selective serotonin reuptake inhibitor used as an antidepressant and antipanic agent in children and adolescents. Sertraline is well tolerated and its safety profile in overdose is favorable. However, sertraline overdose may cause a toxic h... (Source: SafetyLit)
Source: SafetyLit - July 29, 2016 Category: Global & Universal Tags: Alcohol and Other Drugs Source Type: news

Fentanyl can cause serotonin syndrome
3.5 out of 5 stars Serotonin Syndrome Induced by Fentanyl in a Child: Case Report. Robles LA. Clin Neuropharmacol 2015 Sept-Oct;38:206-8. Abstract When many clinicians think of serotonin syndrome (SS), they consider the usual suspects: Selective Serotonin Uptake Inhibitors (SSRIs) Citalopram Fluoxetine Sertraline Escitalopram Paroxetine Serotonin-Norepinephrine Reuptake Inhibitors Venlafaxine Duloxetine Antidepressants Trazodone Buspirone Clomipramine Aside from these common culprits, there are other commonly used drugs whose clear association with serotonin syndrome is less-often realized: Fentanyl Methadon...
Source: The Poison Review - July 8, 2016 Category: Toxicology Authors: Leon Gussow Tags: Medical fentanyl opioid serotonin syndrome Source Type: news

Antidepressants and pregnancy: More research needed
Follow me at @Drmoniquetello For many women, pregnancy and the arrival of a new baby is a joyous time — but not for every woman. Recently, postpartum depression — extreme feelings of sadness and anxiety following the birth of a child — has come out from the shadows. But what about depression during pregnancy? It’s more common than you think: as many as 14% to 23% of pregnant women will experience symptoms of depression. It’s of sufficient public health concern that the U.S. Preventive Services Task Force recommends screening all pregnant women and new moms for depression. However, treating depression during preg...
Source: New Harvard Health Information - May 19, 2016 Category: Consumer Health News Authors: Monique Tello, MD, MPH Tags: Anxiety and Depression Behavioral Health Drugs and Supplements Family Planning and Pregnancy Source Type: news

More than sad: Depression affects your ability to think
When you think of clinical depression, you probably think of feeling sad and down for long periods of time; losing your energy and your interest in things you used to enjoy; sleeping too much or too little, or eating too much or too little. But besides these, depression can actually change your ability to think. It can impair your attention and memory, as well as your information processing and decision-making skills. It can also lower your cognitive flexibility (the ability to adapt your goals and strategies to changing situations) and executive functioning (the ability to take all the steps to get something done). For pe...
Source: New Harvard Health Information - May 6, 2016 Category: Consumer Health News Authors: James Cartreine, PhD Tags: Anxiety and Depression Behavioral Health Brain and cognitive health Mental Health Source Type: news

sertraline, Zoloft
Title: sertraline, ZoloftCategory: MedicationsCreated: 12/31/1997 12:00:00 AMLast Editorial Review: 3/31/2016 12:00:00 AM (Source: MedicineNet Depression General)
Source: MedicineNet Depression General - March 31, 2016 Category: Psychiatry Source Type: news

Sertraline improves Cryptococcus clearance in HIV meningitis
An open-label pilot study has found adjunct treatment with the SSRI antidepressant sertraline is associated with accelerated clearance of Cryptococcus from the cerebrospinal fluid in... (Source: Clinical Neurology News)
Source: Clinical Neurology News - March 25, 2016 Category: Neurology Source Type: news

Sertraline improves Cryptococcus clearance in HIV meningitis
An open-label pilot study has found adjunct treatment with the SSRI antidepressant sertraline is associated with accelerated clearance of Cryptococcus from the cerebrospinal fluid in... (Source: Family Practice News)
Source: Family Practice News - March 25, 2016 Category: Primary Care Source Type: news

Comorbid tics have no effect on response to cognitive-behavioural therapy in youth with obsessive-compulsive disorder
Tic-related obsessive-compulsive disorder (OCD) is a DSM-5 diagnostic subtype that is estimated to occur in 10–40% of cases with childhood onset.1 Studies comparing tic-related and non-tic-related OCD have found consistent differences in sex, onset age, comorbidity and course, but inconsistent differences in OCD symptoms and prevalence of OCD and tics in first-degree relatives.1 ,2 Medication trials have indicated that tic-related OCD is less responsive to sertraline, fluvoxamine and paroxetine; however, tic history appears to have no effect on the res...
Source: Current Awareness Service for Health (CASH) - March 4, 2016 Category: Consumer Health News Source Type: news

Antidepressants linked to suicide and aggression in teens
ConclusionPerhaps the most troubling aspect of this paper is not the increased risk of suicidal thoughts in young people, as that has been known for many years. What is worrying is the researchers’ conclusion that they are unable to tell the true extent of harms from antidepressants, because of poor data collection and availability.RCTs are designed to test the effects of treatments with as little bias as possible. However, if the right data on adverse effects is not collected in the trials, or is not made public, we cannot balance the benefits and risks of treatment in a fair and transparent way. According to the data w...
Source: NHS News Feed - January 28, 2016 Category: Consumer Health News Tags: Mental health Medication Source Type: news

A case of frontotemporal dementia presenting with treatment-refractory psychosis and extreme violence: response to combination of clozapine, medroxyprogesterone, and sertraline - Jha MK, Lambert ES, Beadles BA, Spradling B, Martinez R, Renfro N, Byerly M.
[Abstract unavailable] Language: en... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - October 23, 2015 Category: Global & Universal Tags: Age: Elder Adults Source Type: news

Antidepressant May Help With Premenstrual SyndromeAntidepressant May Help With Premenstrual Syndrome
Administering the antidepressant sertraline at symptom onset may help relieve premenstrual dysphoric disorder in some women. Medscape Medical News (Source: Medscape Psychiatry Headlines)
Source: Medscape Psychiatry Headlines - September 25, 2015 Category: Psychiatry Tags: Psychiatry News Source Type: news

Antidepressant paroxetine study 'under-reported data on harms'
ConclusionThis study stands as a warning about how supposedly neutral scientific research papers may mislead readers by presenting findings in a certain way.The differences between the independent analysis published in the BMJ and the 2001 research paper are stark. They cannot both be right. The "authors" of the 2001 paper appear to have picked outcome measures to suit their results, in the way they present evidence of effectiveness. It has subsequently come to light that the first draft paper was not actually written by the 22 academics named on the paper, but by a "ghostwriter" paid by GSK.The study ...
Source: NHS News Feed - September 17, 2015 Category: Consumer Health News Tags: Medical practice Medication Mental health Pregnancy/child Source Type: news

Antidepressant changes brain differently in depressed, healthy people
Stephen FellerWINSTON-SALEM, N.C., Sept. 4 (UPI) -- The antidepressant sertraline, marketed as Zoloft, was found in a study with nonhuman primates to have different effects on depressed and healthy brains. (Source: Health News - UPI.com)
Source: Health News - UPI.com - September 4, 2015 Category: Consumer Health News Source Type: news