Impact of PTSD treatment on postconcussive symptoms in veterans: a comparison of sertraline, prolonged exposure, and their combination - Porter KE, Stein MB, Grau PP, Kim HM, Powell C, Hoge CW, Venners MR, Smith ER, Martis B, Simon NM, Liberzon I, Rauch SAM.
Many Veterans who served in Iraq and Afghanistan struggle with posttraumatic stress disorder (PTSD) and the effects of traumatic brain injuries (TBI). Some people with a history of TBI report a constellation of somatic, cognitive, and emotional complaints ... (Source: SafetyLit)
Source: SafetyLit - March 22, 2024 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

Research report: a link between sertraline treatment and susceptibility to (mis)information - Piksa M, Noworyta K, Piasecki J, Gundersen A, Kunst J, Morzy M, Rygula R.
Recent research revealed that several psycho-cognitive processes, such as insensitivity to positive and negative feedback, cognitive rigidity, pessimistic judgment bias, and anxiety, are involved in susceptibility to fake news. All of these processes have ... (Source: SafetyLit)
Source: SafetyLit - March 16, 2024 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Effects of transcranial magnetic stimulation combined with sertraline on cognitive level, inflammatory response and neurological function in depressive disorder patients with non-suicidal self-injury behavior - Liu J, Guan J, Xiong J, Wang F.
BACKGROUND: Depressive disorder is a chronic mental illness characterized by persistent low mood as its primary clinical symptom. Currently, psychotherapy and drug therapy stand as the primary treatment modalities in clinical practice, offering a certain d... (Source: SafetyLit)
Source: SafetyLit - March 11, 2024 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

AI Can Predict Response to Early Sertraline for Chronic Major Depression
WEDNESDAY, Feb. 14, 2024 -- Early sertraline treatment response can be predicted using neuroimaging and clinical data in outpatients with chronic major depressive disorder, according to a study published online Feb. 7 in The American Journal of... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - February 14, 2024 Category: Pharmaceuticals Source Type: news

Top psychiatrists warn patients could be put at risk by TV scaremongers 'highlighting the risks of antidepressants' in BBC documentary
In a one case, 18-year-old Dylan Stallan (pictured) took his own life in 2015, two months into a course of the antidepressant sertraline. (Source: the Mail online | Health)
Source: the Mail online | Health - August 19, 2023 Category: Consumer Health News Source Type: news

Abnormal brain spontaneous activity in major depressive disorder adolescents with non-suicidal self injury and its changes after sertraline therapy - Dai L, Zhang X, Yu R, Wang X, Deng F, Li X, Kuang L.
BACKGROUND: Non-suicidal self-injury (NSSI) commonly occurs among adolescents with major depressive disorder (MDD), causing adverse effects on the physical and mental health of the patients. However, the underlying neurobiological mechanism of NSSI in adol... (Source: SafetyLit)
Source: SafetyLit - July 7, 2023 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

Antidepressant taken by millions is being dished out to men struggling with premature ejaculation
The antidepressant sertraline can be life-saver for suicidal Brits or 'destroy their sexual identity' for years after they stop taking it. Experts weigh in after Lewis Capaldi shares his experience. (Source: the Mail online | Health)
Source: the Mail online | Health - June 10, 2023 Category: Consumer Health News Source Type: news

Most antidepressants prescribed for chronic pain lack reliable evidence of efficacy or safety, scientists warn
Largest ever investigation into antidepressants used for chronic pain shows insufficient evidence to determine how effective or harmful they may be.Study reviewed commonly prescribed medications including amitriptyline, duloxetine, fluoxetine, citalopram, paroxetine, and sertraline.One third of people globally are living with long-term pain with many prescribed antidepressants to relieve symptoms.Most antidepressants used for chronic pain are being prescribed with “insufficient” evidence of their effectiveness, scientists have warned.A major investigation into medications used to manage long-term pain found that harms ...
Source: Cochrane News and Events - May 9, 2023 Category: Information Technology Authors: Muriah Umoquit Source Type: news

Speedy Gonzales analysis method in one drop of beverage, for crimes committed with drugs from three different groups - Anilanmert B, Yonar FC.
In this study, a 15  min dilute-and-shoot analysis method was developed for the simultaneous confirmation and quantification of these d... (Source: SafetyLit)
Source: SafetyLit - March 8, 2023 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Interpersonal psychotherapy versus sertraline for women with posttraumatic stress disorder following recent sexual assault: a randomized clinical trial - Proen ça CR, Markowitz JC, Coimbra BM, Cogo-Moreira H, Maciel MR, Mello AF, Mello MF.
BACKGROUND: Sexual assault often triggers posttraumatic stress disorder (PTSD), a potentially chronic severe mental disorder. Most guidelines recommend selective serotonin reuptake inhibitors (SSRIs) and trauma-focused psychotherapies as treatment options.... (Source: SafetyLit)
Source: SafetyLit - October 24, 2022 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

REVEALED: The hidden epidemic of sexual dysfunction which experts blame on SSRI antidepressants
Rebecca Graham is in her early 40s and has had no sensation in her genitals for eight years since she came off the SSRI drug sertraline, which had been prescribed for symptoms of premenstrual syndrome. (Source: the Mail online | Health)
Source: the Mail online | Health - October 1, 2022 Category: Consumer Health News Source Type: news

Sertraline Inhibits CatSper Ca2+ Channels in Human Sperm Sertraline Inhibits CatSper Ca2+ Channels in Human Sperm
This in-vitro study investigated whether selective serotonin reuptake inhibitor antidepressants affect the function of human sperm.Human Reproduction (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - December 8, 2021 Category: Consumer Health News Tags: Ob/Gyn & Women ' s Health Journal Article Source Type: news

Risk of hospitalized depression and intentional self-harm with brand and authorized generic sertraline - Pennap DD, Swain RS, Welch EC, Bohn J, Lyons JG, Dutcher S, Mosholder AD.
BACKGROUND: Recent suggestions of therapeutic inequivalence of brand and generic sertraline have raised concerns about disproportionately higher adverse events among generic users. OBJECTIVE: To assess the impact of confounding in a comparison of t... (Source: SafetyLit)
Source: SafetyLit - October 11, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Patient and clinical factors associated with response to medications for posttraumatic stress disorder - Shiner BR, Gui J, Rozema L, Cornelius SL, Dufort V, Schnurr PP, Watts BV.
OBJECTIVE: Fluoxetine, paroxetine, sertraline, topiramate, and venlafaxine have previously shown efficacy for posttraumatic stress disorder (PTSD) in randomized clinical trials. Two prior studies using Department of Veterans Affairs (VA) medical records da... (Source: SafetyLit)
Source: SafetyLit - October 11, 2021 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

Sertraline hydrochloride for reducing impulsive behaviour in male, repeat-violent offenders (ReINVEST): protocol for a phase IV, double-blind, placebo-controlled, randomised clinical trial - Butler T, Schofield PW, Knight L, Ton B, Greenberg D, Scott RJ, Grant L, Keech AC, Gebski V, Jones J, Ellis A, Weatherburn D, Wilhelm K, Jones A, Churchill A, Allnutt S, Mitchell PB, Chappell D, D'Este C, Villa D, Carr V.
INTRODUCTION: Considerable evidence supports an association between poor impulse control (impulsivity) and violent crime. Furthermore, impulsivity and aggression has been associated with reduced levels of serotonergic activity in the brain. Selective serot... (Source: SafetyLit)
Source: SafetyLit - September 6, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news