Combined Rehabilitation with Alpha Lipoic Acid, Acetyl-L-Carnitine, Resveratrol, and Cholecalciferolin Discogenic Sciatica in Young People: A Randomized Clinical Trial
Conclusions: The combined treatment of rehabilitation and supplements with anti-inflammatory, pain-relieving, and antioxidant action is effective in the treatment of sciatica and can be useful in improving postural stability.PMID:38138300 | PMC:PMC10744495 | DOI:10.3390/medicina59122197 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - December 23, 2023 Category: Universities & Medical Training Authors: Dalila Scaturro Fabio Vitagliani Sofia Tomasello Cristiano Sconza Stefano Respizzi Giulia Letizia Mauro Source Type: research

Isolated Deep Infiltrating Endometriosis of the Sciatic Nerve: A Case Report and Overview of the Literature
We report a case of a 45-year-old woman who experienced a three-year-long and recently exacerbating pain in her right leg, accompanied by a tingling sensation and weakness in her right leg and foot, with difficulty walking. In between regular menstrual bleedings, when her aforementioned symptoms worsened, she had been experiencing mild 10-day extra-cyclical bleeding. Her neurologist's, orthopedist's, and gynecological examinations were unremarkable. Magnetic resonance imaging (MRI) showed an infiltrative lesion on the right sciatic nerve that was immunohistochemically confirmed to be endometriosis. The patient was treated ...
Source: Medicina (Kaunas) - December 23, 2023 Category: Universities & Medical Training Authors: Milena Zamurovic Ana Tomic Katarina Djordjevic Sara Simanic Jelena Sopta Lukas Rasulic Ljubica Simic Jovan Jevtic Olga Nedeljkovic-Arsenovic Marija Rovcanin Source Type: research

US/CT fusion imaging and virtual navigation to guide lumbar intradiscal oxygen-ozone therapy: a pilot study
ConclusionCT/US fusion imaging seems to be a feasible and safe guidance for intradiscal O2/O3 injections, allowing decrease of procedure time and number of CT passes. (Source: Journal of Ultrasound)
Source: Journal of Ultrasound - December 15, 2023 Category: Radiology Source Type: research

Predictors of outcome in sciatica patients following an epidural steroid injection: the POiSE prospective observational cohort study protocol
This study aims to identify factors, including patient characteristics, clinical examination and imaging findings, that help in predicting who does well and who does not after an ESI. The overall objective is to develop a prognostic model to support individualised patient and clinical decision-making regarding ESI. Methods POiSE is a prospective cohort study of 439 patients with sciatica referred by their clinician for an ESI. Participants will receive weekly text messages until 12 weeks following their ESIand then again at 24 weeks following their ESI to collect data on leg pain severity. Questionnaires will be sent to p...
Source: BMJ Open - November 19, 2023 Category: General Medicine Authors: Stynes, S., Snell, K. I., Riley, R. D., Konstantinou, K., Cherrington, A., Daud, N., Ostelo, R., O'Dowd, J., Foster, N. E. Tags: Open access, Epidemiology Source Type: research

I Am Worried I Have Sciatica —What Do I Need to Know?
This JAMA Internal Medicine Patient Page reviews sciatica, its symptoms, and treatment options for those who have it. (Source: JAMA Internal Medicine)
Source: JAMA Internal Medicine - November 13, 2023 Category: Internal Medicine Source Type: research

A network-based approach to explore comorbidity patterns among community-dwelling older adults living alone
This study employed a network-based approach to investigate the comorbidity patterns of community-dwelling older adults living alone. The sample comprised a cross-sectional cohort of adults 65 or older living alone in a Korean city (n = 1041; mean age = 77.7 years, 77.6% women). A comorbidity network analysis that estimates networks aggregated from measures of significant co-occurrence between pairs of diseases was employed to investigate comorbid associations between 31 chronic conditions. A cluster detection algorithm was employed to identify specific clusters of comorbidities. The association strength was expre...
Source: AGE - November 4, 2023 Category: Geriatrics Source Type: research

General practitioners decision-making process to prescribe pain medicines for low back pain: a qualitative study
Conclusions We identified several aspects of decision-making that help explain the current profile of pain medicines prescribed for LBP by GPs. Themes identified by our study could inform future implementation strategies to improve the quality use of medicines for LBP. (Source: BMJ Open)
Source: BMJ Open - October 29, 2023 Category: General Medicine Authors: Ferreira, G. E., Zadro, J., Jones, C., Ayre, J., Lin, C., Richards, B., Needs, C., Abdel Shaheed, C., McLachlan, A., Day, R. O., Maher, C. Tags: Open access, General practice / Family practice Source Type: research

Understanding general practitioners ’ prescribing choices to patients with chronic low back pain: a discrete choice experiment
ConclusionGPs prefer prescribing NSAIDs over opioids for a patient with chronic low back pain regardless of patient factors of comorbidities or the presence of leg pain (i.e. sciatica). (Source: International Journal of Clinical Pharmacy)
Source: International Journal of Clinical Pharmacy - October 26, 2023 Category: Drugs & Pharmacology Source Type: research

Diagnostic accuracy of lumbar CT and MRI in the evaluation of chronic low back pain without red flag symptoms
CONCLUSIONS AND SIGNIFICANCE: CT is as sensitive as lumbar MRI in the evaluation of most of the items analysed, excluding Modic changes, degenerative changes, signal of the disc and disc herniation. In addition, these results are obtained regardless the experience of the radiologist. The rising use of diagnostic medical imaging and the improvement of image quality brings the opportunity of making a second look of abdominal CT in search of causes of LBP. Thereby, inappropriate medical imaging could be avoided (2). In addition, it would allow to reduce MRI waiting list and prioritize other patients with more severe pathology...
Source: Radiologia - October 20, 2023 Category: Radiology Authors: J Martel Villagr án R T Mart ínez-Sánchez E Cebada-Chaparro A L Bueno Horcajadas E P érez-Fernández Source Type: research

Diagnostic accuracy of lumbar CT and MRI in the evaluation of chronic low back pain without red flag symptoms
CONCLUSIONS AND SIGNIFICANCE: CT is as sensitive as lumbar MRI in the evaluation of most of the items analysed, excluding Modic changes, degenerative changes, signal of the disc and disc herniation. In addition, these results are obtained regardless the experience of the radiologist. The rising use of diagnostic medical imaging and the improvement of image quality brings the opportunity of making a second look of abdominal CT in search of causes of LBP. Thereby, inappropriate medical imaging could be avoided (2). In addition, it would allow to reduce MRI waiting list and prioritize other patients with more severe pathology...
Source: Radiologia - October 20, 2023 Category: Radiology Authors: J Martel Villagr án R T Mart ínez-Sánchez E Cebada-Chaparro A L Bueno Horcajadas E P érez-Fernández Source Type: research

Diagnostic accuracy of lumbar CT and MRI in the evaluation of chronic low back pain without red flag symptoms
CONCLUSIONS AND SIGNIFICANCE: CT is as sensitive as lumbar MRI in the evaluation of most of the items analysed, excluding Modic changes, degenerative changes, signal of the disc and disc herniation. In addition, these results are obtained regardless the experience of the radiologist. The rising use of diagnostic medical imaging and the improvement of image quality brings the opportunity of making a second look of abdominal CT in search of causes of LBP. Thereby, inappropriate medical imaging could be avoided (2). In addition, it would allow to reduce MRI waiting list and prioritize other patients with more severe pathology...
Source: Radiologia - October 20, 2023 Category: Radiology Authors: J Martel Villagr án R T Mart ínez-Sánchez E Cebada-Chaparro A L Bueno Horcajadas E P érez-Fernández Source Type: research

Diagnostic accuracy of lumbar CT and MRI in the evaluation of chronic low back pain without red flag symptoms
CONCLUSIONS AND SIGNIFICANCE: CT is as sensitive as lumbar MRI in the evaluation of most of the items analysed, excluding Modic changes, degenerative changes, signal of the disc and disc herniation. In addition, these results are obtained regardless the experience of the radiologist. The rising use of diagnostic medical imaging and the improvement of image quality brings the opportunity of making a second look of abdominal CT in search of causes of LBP. Thereby, inappropriate medical imaging could be avoided (2). In addition, it would allow to reduce MRI waiting list and prioritize other patients with more severe pathology...
Source: Radiologia - October 20, 2023 Category: Radiology Authors: J Martel Villagr án R T Mart ínez-Sánchez E Cebada-Chaparro A L Bueno Horcajadas E P érez-Fernández Source Type: research

Diagnostic accuracy of lumbar CT and MRI in the evaluation of chronic low back pain without red flag symptoms
CONCLUSIONS AND SIGNIFICANCE: CT is as sensitive as lumbar MRI in the evaluation of most of the items analysed, excluding Modic changes, degenerative changes, signal of the disc and disc herniation. In addition, these results are obtained regardless the experience of the radiologist. The rising use of diagnostic medical imaging and the improvement of image quality brings the opportunity of making a second look of abdominal CT in search of causes of LBP. Thereby, inappropriate medical imaging could be avoided (2). In addition, it would allow to reduce MRI waiting list and prioritize other patients with more severe pathology...
Source: Radiologia - October 20, 2023 Category: Radiology Authors: J Martel Villagr án R T Mart ínez-Sánchez E Cebada-Chaparro A L Bueno Horcajadas E P érez-Fernández Source Type: research