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Three-level ACDF versus 3-level laminectomy and fusion: are there differences in outcomes? An analysis of the Quality Outcomes Database cervical spondylotic myelopathy cohort
CONCLUSIONS: In a cohort limited to 3-level fusion surgical procedures, ACDF was associated with reduced blood loss, shorter hospitalization length, and higher routine home discharge rates; however, PCF resulted in lower rates of postoperative dysphagia. The procedures yielded comparably significant improvements in functional status (mJOA score), neck and arm pain, neck pain-related disability, and quality of life at 3, 12, and 24 months. ACDF patients had significantly higher odds of maximum satisfaction (NASS score 1). Given comparable outcomes, patients should be counseled on each approach's complication profile to aid ...
Source: Neurosurgical Focus - September 1, 2023 Category: Neurosurgery Authors: Vardhaan S Ambati Mohamed Macki Andrew K Chan Giorgos D Michalopoulos Vivian P Le Alysha B Jamieson Dean Chou Christopher I Shaffrey Oren N Gottfried Erica F Bisson Anthony L Asher Domagoj Coric Eric A Potts Kevin T Foley Michael Y Wang Kai-Ming Fu Michae Source Type: research

Factors affecting retirement and workforce attrition in neurosurgery: results of a Council of State Neurosurgical Societies national survey
CONCLUSIONS: This study demonstrates that midcareer neurosurgeons may benefit from targeted retention efforts. This effort should focus on maximizing professional satisfaction and financial independence, while decreasing the regulatory burden associated with certification and insurance authorization. End-of-career surgeons should be surveyed to determine factors contributing to resilience and persistence within the neurosurgical workforce.PMID:37657112 | DOI:10.3171/2023.7.JNS231117
Source: Journal of Neurosurgery - September 1, 2023 Category: Neurosurgery Authors: Akshay M Sharma Steven Tenny George L Yang Joseph Cheng John K Ratliff Michael P Steinmetz Satish Krishnamurthy Owoicho Adogwa Karin Swartz Source Type: research

Causal effect of obesity on the probability of employment in women in Turkey
This study aims to investigate the causal effect of obesity on the employment probability of women in Turkey via the instrumental variable approach by using data from the 2018 Turkey and Demographic Health Survey. Obesity prevalence in the area of living and the overweight status of the oldest child, which are the most common types of instruments seen in the literature, are used as instruments. Consistent with the OLS result, the 2SLS estimate indicates that obese women are statistically significantly less likely to be employed when the overweight status of the child is used as an instrument. On the other hand, the statist...
Source: Economics and Human Biology - August 31, 2023 Category: Biology Authors: Didem Pekkurnaz Source Type: research

Elemental exchange: Bioisosteric replacement of phosphorus by boron in drug design
Eur J Med Chem. 2023 Aug 25;260:115761. doi: 10.1016/j.ejmech.2023.115761. Online ahead of print.ABSTRACTContinuous efforts are being directed toward the employment of boron in drug design due to its advantages and unique characteristics including a plethora of target engagement modes, lower metabolism, and synthetic accessibility, among others. Phosphates are components of multiple drug molecules as well as clinical candidates, since they play a vital role in various biochemical functions, being components of nucleotides, energy currency- ATP as well as several enzyme cofactors. This review discusses the unique chemistry ...
Source: European Journal of Medicinal Chemistry - August 31, 2023 Category: Chemistry Authors: Namrashee V Mehta Arundhati Abhyankar Mariam S Degani Source Type: research

Current status of infectious diseases among migrants and non-citizens in Malaysia
Trop Biomed. 2023 Jun 1;40(2):138-151. doi: 10.47665/tb.40.2.003.ABSTRACTThe mass movement of migrants to Malaysia for employment is one of the factors contributing to the emergence and re-emergence of infectious diseases in this country. Despite mandatory health screening for migrants seeking employment, prevalence records of infectious diseases amongst migrant populations in Malaysia are still within negligible proportions. Therefore, the present review highlights the incidence, mortality and overall status of infectious diseases amongst migrants' populations in Malaysia, which maybe be useful for impeding exacerbation o...
Source: Tropical Biomedicine - August 31, 2023 Category: Tropical Medicine Authors: N W S Mohd Putera A S Azman S N Mohd Zain H Yahaya J W Lewis N Sahimin Source Type: research

Lessons Learned From Contact Tracing During the COVID-19 Pandemic: Public Health Students' Experiences in the Field
This study employed a qualitative thematic approach to capture 11 graduate-level public health students' experiences, motivations, challenges, and recommendations on contact tracing procedures as DOH contract tracers. In-depth interview questions focused on students' interest in public health, experiences as a contact tracer, patient/case interactions, and personal outlook on the COVID-19 pandemic. The COVID-19 pandemic brought new experiences and challenges for public health students employed by local health departments as contact tracers. Three categories and subthemes emerged from interviews: (1) motivations to work as ...
Source: Primary Care - August 31, 2023 Category: Primary Care Authors: Tienna Fenton Talegria Brown Elena Bastida Source Type: research

Current status of infectious diseases among migrants and non-citizens in Malaysia
Trop Biomed. 2023 Jun 1;40(2):138-151. doi: 10.47665/tb.40.2.003.ABSTRACTThe mass movement of migrants to Malaysia for employment is one of the factors contributing to the emergence and re-emergence of infectious diseases in this country. Despite mandatory health screening for migrants seeking employment, prevalence records of infectious diseases amongst migrant populations in Malaysia are still within negligible proportions. Therefore, the present review highlights the incidence, mortality and overall status of infectious diseases amongst migrants' populations in Malaysia, which maybe be useful for impeding exacerbation o...
Source: Tropical Biomedicine - August 31, 2023 Category: Tropical Medicine Authors: N W S Mohd Putera A S Azman S N Mohd Zain H Yahaya J W Lewis N Sahimin Source Type: research

Temporal decline in serum PFAS concentrations among metropolitan firefighters: Longitudinal study on post-exposure changes following PFAS foam cessation
This study provides evidence for a declining temporal trend in serum PFAS concentrations among metropolitan firefighters following workplace interventions that involved the removal of PFAS-containing foams.PMID:37651929 | DOI:10.1016/j.envint.2023.108167
Source: Environment International - August 31, 2023 Category: Environmental Health Authors: Yonatal Mesfin Tefera Sharyn Gaskin Krystle Mitchell David Springer Simon Mills Source Type: research