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Drug: Acetic Acid

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Total 4747 results found since Jan 2013.

Quality consistency evaluation of chemical composition and pharmacology of Shaoyao-Gancao decoction dispensing granules and traditional decoction
This study presents a method for evaluating the quality consistency of DGCM and TD of SGD, offering novel insights into the evaluation of consistency between DGCM and TD.PMID:37736670 | DOI:10.1002/bmc.5745
Source: Biomedical Chromatography : BMC - September 22, 2023 Category: Biomedical Science Authors: Fengyu Dong Mengdi Xie Manwen Xu Lu Lu Yan Miao Panpan Zhang Xiaopeng Li Xinjing Gui Ruixin Liu Source Type: research

Synthesis of functionalized alkenes via Cu(I)-catalysed allylation of acetanilides using Morita-Baylis-Hillman bromides
Org. Biomol. Chem., 2023, Accepted Manuscript DOI: 10.1039/D3OB01480K, PaperRamesh Kumar Vishwakarma, Krishna Nand Singh An easy access to functionalized alkenes has been developed by the C-H functionalization of anilides with Morita-Baylis-Hillman (MBH) bromides in the presence of copper chloride, TBHP and acetic acid. Unsubstituted... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Organic and Biomolecular Chemistry - September 21, 2023 Category: Molecular Biology Authors: Ramesh Kumar Vishwakarma Source Type: research

Endophytic Fungus Talaromyces sp. MR1 Promotes the Growth and Cadmium Uptake of Arabidopsis thaliana L. Under Cadmium Stress
Curr Microbiol. 2023 Sep 21;80(11):346. doi: 10.1007/s00284-023-03453-3.ABSTRACTEndophytes play essential roles in plant growth under metal(loid)s stress. An endophytic fungus strain MR1 was isolated from the roots of Miscanthus floridulus collected from a lead-zinc mining area (Huayuan, China), which could produce indole-3-acetic acid and have Cadmium (Cd) tolerance. Further 18S rRNA sequencing analysis showed that it was highly similar (99.83%) to Talaromyces pinophilus. In pot experiments, we explored the effects of strain MR1 on the growth and Cd uptake of a wide-type Arabidopsis thaliana under low (LC) and high (HC) C...
Source: Current Microbiology - September 21, 2023 Category: Microbiology Authors: Yunhua Xiao Rui Chen Liang Chen Bo Yang Lihong Jiang Jun Fang Source Type: research

Behaviour of organic adsorbable corrosion inhibitors containing N, S, and O functional groups on aluminium in weak acetic acid solutions as simulated HVDC cooling water
New J. Chem., 2023, Advance Article DOI: 10.1039/D3NJ03389A, CommunicationZhen Wang, Kai Xiao, Guoqing Zhang, Xue Han, Zhihong Cai, Zhen Shao, Youping Fan, Shengping Wang Functional groups of organic inhibitors containing N, O, S with lone-pair electrons chemically bond with aluminum to inhibit corrosion. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - New J. Chem. latest articles - September 20, 2023 Category: Chemistry Authors: Zhen Wang Source Type: research

Co-administration of Thymoquinone and Propolis in Liposomal Formulations as a Potential Approach for Treatment of Acetic Acid-Induced Ulcerative Colitis: Physiological and Histopathological Analysis
This study is aimed at assessing the potential of liposomal formulations of TQ and Egyptian PP in combination therapy on improving their therapeutic efficacy against ulcerative colitis in order to maximize the potential of their beneficial clinical effects. Clinical, biochemical, and histological evaluations of colonic mucosal damage and inflammation were evaluated. The results exhibited a significant increase in tissue MDA, TNFα, and nitrite levels with activation of caspase-3 in the acetic acid-induced colitis group, which is predominantly downregulated in the treatment groups. The prepared formulations of TQ and PP rev...
Source: AAPS PharmSciTech - September 19, 2023 Category: Drugs & Pharmacology Authors: Eman Alaaeldin Hesham Refaat Entesar Ali Saber Neven Makram Aziz Nehad M Reda Abdel-Maqsoud Mohammed Mustafa Abd El Aleem Maha Yehia Kamel Fatma M Mady Source Type: research

Metal-Free Electrocatalytic Diacetoxylation of Alkenes
Angew Chem Int Ed Engl. 2023 Sep 19:e202311539. doi: 10.1002/anie.202311539. Online ahead of print.ABSTRACT1,2-Dioxygenation of alkenes leads to a structural motif ubiquitous in organic synthons, natural products and active pharmaceutical ingredients. Straightforward and green synthesis protocols starting from abundant raw materials are required for facile and sustainable access to these crucial moieties. Especially industrially abundant aliphatic alkenes have proven to be arduous substrates in sustainable 1,2-dioxygenation methods. Here, we report a highly efficient electrocatalytic diacetoxylation of alkenes under ambien...
Source: Angewandte Chemie - September 19, 2023 Category: Chemistry Authors: Jef R Vanhoof Pieter J De Smedt Jan Derhaeg Rob Ameloot Dirk De Vos Source Type: research

Effects on gene expression during maize-Azospirillum interaction in the presence of a plant-specific inhibitor of indole-3-acetic acid production
Genet Mol Biol. 2023 Sep 18;46(3 Suppl 1):e20230100. doi: 10.1590/1678-4685-GMB-2023-0100. eCollection 2023.ABSTRACTAmongst the sustainable alternatives to increase maize production is the use of plant growth-promoting bacteria (PGPB). Azospirillum brasilense is one of the most well-known PGPB being able to fix nitrogen and produce phytohormones, especially indole-3-acetic acid - IAA. This work investigated if there is any contribution of the bacterium to the plant's IAA levels, and how it affects the plant. To inhibit plant IAA production, yucasin, an inhibitor of the TAM/YUC pathway, was applied. Plantlets' IAA concentra...
Source: Mol Biol Cell - September 19, 2023 Category: Molecular Biology Authors: Eliandro Espindula Edilena Reis Sperb Brenda Mor V ânia Carla Silva Pankievicz Thalita Regina Tuleski Michelle Zibetti Tadra-Sfeir Paloma Bonato Camila Scheid Josias Merib Emanuel Maltempi de Souza Luciane Maria Pereira Passaglia Source Type: research

Co-administration of Thymoquinone and Propolis in Liposomal Formulations as a Potential Approach for Treatment of Acetic Acid-Induced Ulcerative Colitis: Physiological and Histopathological Analysis
This study is aimed at assessing the potential of liposomal formulations of TQ and Egyptian PP in combination therapy on improving their therapeutic efficacy against ulcerative colitis in order to maximize the potential of their beneficial clinical effects. Clinical, biochemical, and histological evaluations of colonic mucosal damage and inflammation were evaluated. The results exhibited a significant increase in tissue MDA, TNFα, and nitrite levels with activation of caspase-3 in the acetic acid-induced colitis group, which is predominantly downregulated in the treatment groups. The prepared formulations of TQ and PP rev...
Source: AAPS PharmSciTech - September 19, 2023 Category: Drugs & Pharmacology Authors: Eman Alaaeldin Hesham Refaat Entesar Ali Saber Neven Makram Aziz Nehad M Reda Abdel-Maqsoud Mohammed Mustafa Abd El Aleem Maha Yehia Kamel Fatma M Mady Source Type: research

Discovery of (S)-flurbiprofen-based novel azine derivatives as prostaglandin endoperoxide synthase-II inhibitors: Synthesis, in-vivo analgesic, anti-inflammatory activities, and their molecular docking
Bioorg Chem. 2023 Sep 12;141:106847. doi: 10.1016/j.bioorg.2023.106847. Online ahead of print.ABSTRACTThe anti-inflammatory and analgesic drugs currently used are associated with several adverse effects and found to be highly unsafe for long-term use. Currently, nineteen novel bis-Schiff base derivatives (1-19) of flurbiprofen have been designed, prepared and assessed for in-vivo analgesic, anti-inflammatory and in vivo acute toxicity evaluation. The structures of the acquired compounds were deduced through modern spectroscopic techniques including HR-ESI-MS, 13C-, and 1H NMR. Amongst the series, compounds 7, 9, and 10 att...
Source: Bioorganic Chemistry - September 18, 2023 Category: Chemistry Authors: Aftab Alam Mumtaz Ali None Zainab Abdul Latif Najeeb Ur Rehman Abdul Jabbar Shah Irfan Amir Khan Muhammad Ayaz Sajjad Ur Rahman Ahmed Al-Harrasi Manzoor Ahmad Source Type: research

The G protein-coupled receptor COLD1 promotes chilling tolerance in maize during germination
In this study, a chilling-tolerance gene in maize, ZmCOLD1, was cloned and characterized. This gene encodes a G protein-coupled receptor that is localized to the plasma membrane and the endoplasmic reticulum. A single nucleotide polymorphism (SNP) in ZmCOLD1, SNP2738, was found to confer chilling tolerance and to have promoted maize adaptations during speciation from teosinte. Overexpression of the excellent haplotype ZmCOLD1Hap11 significantly enhanced chilling tolerance, whereas knocking down ZmCOLD1 increased sensitivity to low temperatures during the germination and seedling stages. ZmCOLD1 was associated with an influ...
Source: International Journal of Biological Macromolecules - September 16, 2023 Category: Biochemistry Authors: Yu Zhou Hong Zhang Simeng Zhang Jiayue Zhang Hong Di Lin Zhang Ling Dong Qing Lu Xing Zeng Xianjun Liu Naifu Zhang Zhenhua Wang Source Type: research

Two-dimensional chromatography for enantiomeric analysis of mitotane and its metabolite o,p'-DDA in patients with adrenocortical carcinoma indicates enantioselective metabolism
In this study, we analyzed the enantiomers of mitotane and o,p'-DDA in the plasma of patients by a newly developed chiral-phase method employed in two-dimensional chromatography. Important differences were observed in the ratio of (S)/(R)-mitotane, which varied substantially from 1:1.2 to 1:10 whereas the (S)/(R)-o,p'-DDA ratio was relatively conserved, at approximately 2:1. These findings provide evidence for the enantioselective metabolism and provide a method for further analyses of mitotane and metabolites, which can explain the variation in the therapeutic response.PMID:37713949 | DOI:10.1016/j.bioorg.2023.106835
Source: Bioorganic Chemistry - September 15, 2023 Category: Chemistry Authors: Gabriela Stadler Alan de Almeida Veiga Claudia Rita Corso Camila Bach de Assis Beatriz de Toledo Nogueira Lucia Regina Rocha Martins Beatriz Cruz Bonk Fl ávia Lada Degaut Pontes Bonald Cavalcante de Figueiredo Lauro Mera de Souza Source Type: research

Screening groundnut rhizobia for multiple plant growth promoting activities in Ethiopia
Rhizobia could exhibit plant growth-promoting mechanisms besides nitrogen fixation. In search of efficient rhizobia with multiple PGP traits, 72 groundnut nodulating rhizobia isolates were screened in vitro for their plant growth promoting traits like phosphate solubilization, production of indole acetic acid, ammonia, hydrogen cyanide, production of different hydrolytic enzymes and antifung...
Source: African Journal of Microbiology Research - September 14, 2023 Category: Microbiology Source Type: research