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Total 127160 results found since Jan 2013.
Normal values of left atrial size and strain analyzed by the dedicated speckle-tracking echocardiography in Chinese population
Kardiol Pol. 2023 Sep 18. doi: 10.33963/v.kp.97479. Online ahead of print.NO ABSTRACTPMID:37718581 | DOI:10.33963/v.kp.97479
Source: Kardiologia Polska - September 18, 2023 Category: Cardiology Authors: Lei Li Chunyuan You Jun Yang Junfei Shen Pingyang Zhang Source Type: research
Associations between longer leukocyte telomere length and increased lung cancer risk among never smokers in urban China
CONCLUSIONS: Longer pre-diagnostic leukocyte telomere length is associated with increased lung cancer risk among never smokers.IMPACT: Our findings firmly support the role of longer telomeres in lung carcinogenesis.PMID:37721487 | DOI:10.1158/1055-9965.EPI-23-0881
Source: Cancer Control - September 18, 2023 Category: Cancer & Oncology Authors: Jason Yy Wong Xiao-Ou Shu Wei Hu Batel Blechter Jianxin Shi Kevin Wang Richard Cawthon Qiuyin Cai Gong Yang Mohammad L Rahman Bu-Tian Ji Yutang Gao Wei Zheng Nathaniel Rothman Qing Lan Source Type: research
A case study of unavoidable accidents of autonomous vehicles
Conclusions: Collision accidents will still occur even with perfect autonomous driving technology. We used the prospective method to investigate scenarios and characteristics of unavoidable accidents of autonomous vehicles. The time-limit type and the space-limit type were identified as two categories of unavoidable accidents. For the time-limit unavoidable accidents, the time from perceiving hazard to collision is typically not longer than 1.5s. The characteristics of unavoidable accidents and the estimated pre-crash warning time can provide some reference for establishing future occupant protection strategies. This study...
Source: Traffic Injury Prevention - September 18, 2023 Category: Accident Prevention Authors: Zhiwei Sun Miao Lin Wentao Chen Bing Dai Pengfei Ying Qing Zhou Source Type: research
Diagnostic efficiency among Eu-/C-/ACR-TIRADS and S-Detect for thyroid nodules: a systematic review and network meta-analysis
CONCLUSION: Among four ultrasound risk stratification options, this systemic review preliminarily proved that C-TIRADS possessed favorable diagnostic performance for thyroid nodules.SYSTEMATIC REVIEW REGISTRATION: https://www.crd.york.ac.uk/prospero, CRD42022382818.PMID:37720531 | PMC:PMC10501732 | DOI:10.3389/fendo.2023.1227339
Source: Cancer Control - September 18, 2023 Category: Cancer & Oncology Authors: Longtao Yang Cong Li Zhe Chen Shaqi He Zhiyuan Wang Jun Liu Source Type: research
Red cell distribution width-a potential prognostic indicator for colorectal cancer patients after radical resection in China
CONCLUSIONS: Our findings demonstrate that preoperative RDW may represent a simple and powerful prognostic factor for CRC patients after radical resection. Integrating RDW into clinical practice may better inform the prognosis and optimize therapeutic approaches for patients with CRC.PMID:37720452 | PMC:PMC10502564 | DOI:10.21037/jgo-23-54
Source: Cancer Control - September 18, 2023 Category: Cancer & Oncology Authors: Weiwei Zhao Xuefang Shen Qing Hua Liu Yang Ru Zhou Changming Zhou Pingbo Xu Source Type: research
< em > IL1RL1 < /em > polymorphisms rs12479210 and rs1420101 are associated with increased lung cancer risk in the Chinese Han population
Conclusion: Our findings suggest that IL1RL1 genetic variants (rs12479210 and rs1420101) are associated with an increased lung cancer risk in the Chinese Han population. These risk variants may serve as biomarkers for the prevention and treatment of lung cancer.PMID:37719702 | PMC:PMC10500304 | DOI:10.3389/fgene.2023.1183528
Source: Cancer Control - September 18, 2023 Category: Cancer & Oncology Authors: Qi Li Chan Zhang Yujing Cheng Xin Yang Wanlu Chen Kunhua He Mingwei Chen Source Type: research
Identification of quality markers for < em > Cyanotis arachnoidea < /em > and analysis of its physiological mechanism based on chemical pattern recognition, network pharmacology, and experimental validation
In this study, ultra-high-performance liquid chromatography (UHPLC) fingerprint combined with chemical pattern recognition were performed, and four differential components were screened out as quality markers, including 20-Hydroxyecdysone, 3-O-acetyl-20-hydroxyecdysone, Ajugasterone C, and 2-O-acetyl-20-hydroxyecdysone. Network pharmacology analysis revealed 107 therapeutic target genes of Cyanotis arachnoidea in DM treatment, and the key targets were Akt1, TNF, IL-6, MAPK3, and JUN. The hypoglycemic mode of action of Cyanotis arachnoidea may be mediated by tumor necrosis factor (TNF) signaling, cancer, insulin resistance,...
Source: Cancer Control - September 18, 2023 Category: Cancer & Oncology Authors: Jingnan Hu Yu Feng Baolin Li Fengxia Wang Qi Qian Wei Tian Liying Niu Xinguo Wang Source Type: research
An integrated data- and theory-driven crash severity model
Accid Anal Prev. 2023 Sep 16;193:107282. doi: 10.1016/j.aap.2023.107282. Online ahead of print.ABSTRACTFor crash severity modeling, researchers typically view theory-driven models and data-driven models as different or even conflicting approaches. The reason is that the machine-learning models offer good predictability but weak interpretability, while the latter has robust interpretability but moderate predictability. In order to alleviate the tension between them, this study proposes an integrated data- and theory-driven crash-severity model, known as Embedded Fusion model based on Text Vector Representations (TVR-EF), by...
Source: Accident; Analysis and Prevention. - September 18, 2023 Category: Accident Prevention Authors: Dongjie Liu Dawei Li N N Sze Hongliang Ding Yuchen Song Source Type: research
Metagenomics reveals the effects of glyphosate on soil microbial communities and functional profiles of C and P cycling in the competitive vegetation control process of Chinese fir plantation
In this study, shotgun metagenomic sequencing was used to determine the abundance and diversity of microbial communities and functional genes after foliar application of glyphosate for 1, 2, 3 and 4 months in a Chinese fir plantation. The results showed that glyphosate increased the copy numbers (qPCR) of 16s rRNA gene for 16.9%, improved the bacterial diversity (Shannon index) and complexity of bacterial co-occurrence network, and changed the abundances of some bacterial and fungal taxa, but had no effects on ITS gene copy numbers, fungal Shannon index, and bacterial and fungal communities (PCoA). Glyphosate application s...
Source: Environmental Research - September 18, 2023 Category: Environmental Health Authors: Song Wang Yuanyuan Han Xiaoyu Wu Honggang Sun Source Type: research
Potential selection for lipid kinase activity and spermatogenesis in Henan native pig breeds and growth shaping by introgression of European genes
CONCLUSIONS: Admixture of North China, East China and foreign pigs contributed to high genetic diversity of Henan local pigs. Ontology terms associated with lipid kinase activity and spermatogenesis and growth shaping by introgression of European genes in Henan pigs were identified through selective sweep analyses.PMID:37723431 | DOI:10.1186/s12711-023-00841-y
Source: Genet Sel Evol - September 18, 2023 Category: Genetics & Stem Cells Authors: Ruimin Qiao Xinjian Li Ole Madsen Martien A M Groenen Pan Xu Kejun Wang Xuelei Han Gaiying Li Xiuling Li Kui Li Source Type: research
The mechanism of Plantaginis Semen in the treatment of diabetic nephropathy based on network pharmacology and molecular docking technology
CONCLUSION: PS can have the treatment on DN through CASP3. Quercetin, as one of the nine active ingredients, can be bounded to CASP3 to inhibit apoptosis in DN. PS can also take action on DN probably through many pathways. The role of PS on DN through other pathways still needs to be further elaborated.PMID:37718520 | DOI:10.2174/1871530323666230915100355
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - September 18, 2023 Category: Endocrinology Authors: Linlin He Kai Shen Lei He Yuqing Chen Zhiyuan Tang Source Type: research
Air nanobubble water improves plant uptake and tolerance toward cadmium in phytoremediation
This study found that diluted air NBs (25% concentration) boosted cadmium uptake of A. philoxeroides by 17.39%. They also enhanced growth (25-50%) and photosynthetic pigments (10-20%) even at low cadmium levels (0.1 mM). Furthermore, the incorporation of 25% air NBs has been demonstrated to significantly amplify the performance of key antioxidant enzymes, such as superoxide dismutase and catalase, alongside heightened levels of crucial antioxidants such as malondialdehyde. This heightened activity of antioxidant defenses offers a compelling explanation for the potential amelioration of cadmium toxicity and concurrent enhan...
Source: Environmental Pollution - September 18, 2023 Category: Environmental Health Authors: Dajiang Yan Shan Xue Zhibin Zhang Guodong Xu Yanhao Zhang Jianan Gao Wen Zhang Source Type: research
Comparison of eltrombopag and avatrombopag in the treatment of refractory/relapsed aplastic anemia: a single-center retrospective study in China
CONCLUSION: With worse liver or renal function, AVA had a similar OR/CR rate but a shorter median time to response and fewer adverse events for patients with relapsed/refractory AA.PMID:37719987 | PMC:PMC10503291 | DOI:10.1177/20406207231191310
Source: Adv Data - September 18, 2023 Category: Epidemiology Authors: Zhuxin Zhang Qinglin Hu Chen Yang Miao Chen Bing Han Source Type: research
Prevalence and associated factors of hyperuricemia among Chinese patients with diabetes: a cross-sectional study
CONCLUSION: Hyperuricemia is highly prevalent in patients with diabetes, especially in males. In addition to traditionally associated factors, fenofibrate and SGLT-2 inhibitors were also associated with the risk of hyperuricemia.REGISTRATION: The study protocol was registered in the Chinese Clinical Trial Registry (http://www.chictr.org.cn/), and the registration number was ChiCTR 2100042742.PMID:37719790 | PMC:PMC10501065 | DOI:10.1177/20420188231198620
Source: Adv Data - September 18, 2023 Category: Epidemiology Authors: Shiyi Sun Lihong Chen Dawei Chen Yan Li Guanjian Liu Lin Ma Jun Li Fangwei Cao Xingwu Ran Source Type: research
Recent progress in epidemiology, clinical features, and therapy of multiple sclerosis in China
Ther Adv Neurol Disord. 2023 Sep 15;16:17562864231193816. doi: 10.1177/17562864231193816. eCollection 2023.ABSTRACTMultiple sclerosis (MS) is a demyelinating disease of the central nervous system characterized by inflammation, demyelination, and neurodegeneration. It mainly affects young adults, imposing a heavy burden on families and society. The epidemiology, clinical features, and management of MS are distinct among different countries. Although MS is a rare disease in China, there are 1.4 billion people in China, so the total number of MS patients is not small. Because of the lack of specific diagnostic biomarkers for ...
Source: Adv Data - September 18, 2023 Category: Epidemiology Authors: Meng Wang Caiyun Liu Meijuan Zou Zixuan Niu Jie Zhu Tao Jin Source Type: research
